Results 141 to 150 of about 253,295 (266)

In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions

Nature Communications
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and shear force that can induce cellular damage and ...
Georgia K. Atkin-Smith, Jascinta P. Santavanond, Amanda Light, Joel S. Rimes, Andre L. Samson, Jeremy Er, Joy Liu, Darryl N. Johnson, Mélanie Le Page, Pradeep Rajasekhar, Raymond K. H. Yip, Niall D. Geoghegan, Kelly L. Rogers, Catherine Chang, Vanessa L. Bryant, Mai Margetts, M. Cristina Keightley, Trevor J. Kilpatrick, Michele D. Binder, Sharon Tran, Erinna F. Lee, Walter D. Fairlie, Dilara C. Ozkocak, Andrew H. Wei, Edwin D. Hawkins, Ivan K. H. Poon   +25 more
doaj   +1 more source

Flow cytometric analysis of circulating endothelial cells and endothelial progenitor cells in pediatric solid tumors: prognostic impact on treatment response and survival. [PDF]

Cancer Immunol Immunother, 2021
Sayed HAR, Hetta HF, Shafik EA, Zahran AM.   +3 more
europepmc   +1 more source

Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction

Advanced Functional Materials, EarlyView.
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li, Xin‐Yi Qian, Zi‐Yuan Li, Hao‐Wen Li, Poh‐Ching Tan, Chenghuizi Hu, Jiajun Jin, Shuang‐Bai Zhou, Qing‐Feng Li, He Tian, Junji Zhang, Itamar Willner   +11 more
wiley   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John, Caitlyn Dang, Nidhi Reddy, Calvin Chao, Karen J. Ho, Bin Jiang   +5 more
wiley   +1 more source

The detection of circulating endothelial cells in human septic shock

, 2000
Mbithe Mutunga, A. Gascoigne, Anna Batchelor, R. Bullock, Barbara Fulton, James Gillespie, Simon Baudouin   +6 more
openalex   +1 more source

Transplantation of Circulating Endothelial Progenitor Cells Restores Endothelial Function of Denuded Rabbit Carotid Arteries [PDF]

, 2004
Tongrong He, Leslie Smith, Sean C. Harrington, Karl A. Nath, Noel M. Caplice, Zvonimir S. Katušić   +5 more
openalex   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Shape dynamics and migration of branched cells on complex networks [PDF]

arXiv
Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues. In another example, to properly irrigate the tissues, blood vessels bifurcate thereby forcing the branching of ...
arxiv  

Circulating Humoral Factors and Endothelial Progenitor Cells in Patients With Differing Coronary Collateral Support [PDF]

, 2004
Pier D. Lambiase, Richard J. Edwards, Prodromos Anthopoulos, Salman Rahman, Yong Meng, C. Bucknall, Simon Redwood, Jeremy D. Pearson, Michael Marber   +8 more
openalex   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source