Results 21 to 30 of about 367,441 (304)

Longitudinal study of circulating protein biomarkers in inflammatory bowel disease [PDF]

Journal of Proteomics, 2015
Inflammatory bowel diseases (IBDs) are chronic and progressive inflammatory disorders of the gastrointestinal tract. In IBD, protein serological biomarkers could be relevant tools for assessing disease activity, performing early-stage diagnosis and managing the treatment.
Emilie Viennois, Mark T. Baker, Bo Xiao, Lixin Wang, Hamed Laroui, Didier Merlin   +5 more
openaire   +2 more sources

Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer [PDF]

Scientific Reports, 2018
AbstractAlthough inflammation is central to gallbladder cancer (GBC) development and proliferation, no study has systematically investigated circulating inflammatory proteins and patient survival. We aimed to examine whether the circulating levels of inflammatory proteins is associated with all-cause mortality among such patients.
Zhiwei Liu, Troy J. Kemp, Yu-Tang Gao, Amanda Corbel, Emma E. McGee, Juan Carlos Roa, Bingsheng Wang, Juan Carlos Araya, Ming-Chang Shen, Asif Rashid, Ann W. Hsing, Allan Hildesheim, Catterina Ferreccio, Ruth M. Pfeiffer, Ligia A. Pinto, Jill Koshiol   +15 more
openaire   +3 more sources

The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic Analysis

Journal of Pain Research
Shaoru Lin,1 Changwu Wu,2,3 Yimin Pan2 1Department of Orthopedics, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2Department of Neurosurgery, Xiangya Hospital, Central South ...
Lin S, Wu C, Pan Y
doaj   +3 more sources

Circulating Profile of ECM-Related Proteins as Diagnostic Markers in Inflammatory Bowel Diseases

Journal of Clinical Medicine, 2022
The aim of our research was to find new biomarkers that could be potentially used in the diagnosis, differentiation and monitoring of inflammatory bowel diseases (IBD). Since extracellular matrix (ECM) remodeling contributes to the pathological changes occurring in IBD, the serum profile of ECM-related proteins may reflect disease activity in the ...
Katarzyna Komosinska-Vassev, Aleksandra Kałużna, Agnieszka Jura-Półtorak, Alicja Derkacz, Krystyna Olczyk   +4 more
openaire   +2 more sources

Differential regulation of circulating levels of molecular chaperones in patients undergoing treatment for periodontal disease. [PDF]

, 2007
Evidence is emerging that molecular chaperones, in addition to their intracellular protein folding actions, can act as intercellular signaling proteins with an ability to modulate leukocyte function. Recent evidence has also shown that these proteins can
Alireza Shamaei-Tousi, Francesco D'Aiuto, D'Aiuto Francesco, D'Aiuto, F, Coates, ARM, Henderson Brian, Henderson, B, Donos, N, Brian Henderson, Shamaei-Tousi Alireza, Coates, AR, Nibali Luigi, Coates Anthony R. M., Donos Nikos, Mohamed Parkar, Nibali, L, Parkar, M, Parkar Mohamed, Luigi Nibali, Andrew Steptoe, Anthony R M Coates, Steptoe Andrew, Steptoe, A, Shamaei-Tousi, A, Nikos Donos   +24 more
core   +1 more source

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes [PDF]

Nature Medicine, 2019
Chronic inflammation is postulated to be involved in the development of end-stage renal disease in diabetes, but which specific circulating inflammatory proteins contribute to this risk remain unknown. To study this, we examined 194 circulating inflammatory proteins in subjects from three independent cohorts with type 1 and type 2 diabetes.
Monika A. Niewczas, Meda E. Pavkov, Jan Skupien, Adam Smiles, Zaipul I. Md Dom, Jonathan M. Wilson, Jihwan Park, Viji Nair, Andrew Schlafly, Pierre-Jean Saulnier, Eiichiro Satake, Christopher A. Simeone, Hetal Shah, Chengxiang Qiu, Helen C. Looker, Paolo Fiorina, Carl F. Ware, Jennifer K. Sun, Alessandro Doria, Matthias Kretzler, Katalin Susztak, Kevin L. Duffin, Robert G. Nelson, Andrzej S. Krolewski   +23 more
openaire   +4 more sources

Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [PDF]

, 2015
Background: Clinical decision and patient care management in inflammatory bowel diseases is largely based on the assessment of clinical symptoms, while the biomarkers currently in use poorly reflect the actual disease activity.
Oikonomopoulos, A, Hommes, DW, Iliopoulos, D, Mahurkar, S, Koukos, G, Polytarchou, C, Touroutoglou, A   +6 more
core   +1 more source

An inflammatory cascade leading to hyperresistinemia in humans. [PDF]

PLoS Medicine, 2004
Obesity, the most common cause of insulin resistance, is increasingly recognized as a low-grade inflammatory state. Adipocyte-derived resistin is a circulating protein implicated in insulin resistance in rodents, but the role of human resistin is ...
Michael Lehrke, Muredach P Reilly, Segan C Millington, Nayyar Iqbal, Daniel J Rader, Mitchell A Lazar   +5 more
doaj   +1 more source

Poly(I:C)-Induced Mesenchymal Stem Cells Protect the Kidney Against Ischemia/Reperfusion Injury via the TLR3/PI3K Pathway

Frontiers in Medicine, 2021
Objective: To investigate the effect and protective mechanism of mesenchymal stem cell subpopulations on acute kidney injury by establishing a mouse model of renal ischemia-reperfusion injury.Methods: Male C57BL/6 mice were randomly divided into five ...
Tian Chen, Tian Chen, Yamei Jiang, Yamei Jiang, Shihao Xu, Shihao Xu, Yin Celeste Cheuk, Yin Celeste Cheuk, Jiyan Wang, Cheng Yang, Cheng Yang, Ruiming Rong, Ruiming Rong   +12 more
doaj   +1 more source

Lifecourse social position and D-dimer; findings from the 1958 British birth cohort [PDF]

, 2014
The aim is to examine the association of lifecourse socioeconomic position (SEP) on circulating levels of D-dimer. Data from the 1958 British birth cohort were used, social class was determined at three stages of respondents' life: at birth, at 23 and at
Lowe, Gordon, Kumari, Meena, Faiza Tabassum, Power Chris, Faiza Tabassum (429554), Tabassum, Faiza, Power, C, Lowe Gordon, Gordon Lowe (259949), Ann Rumley, Ann Rumley (90044), Chris Power, Kumari Meena, Meena Kumari, Meena Kumari (95278), Power, Chris, David P. Strachan (110302), Strachan, David P., Tabassum Faiza, Kumari, M, Tabassum, F, Strachan, DP, David P Strachan, Rumley, Ann, Strachan David P., Strachan, David P, Chris Power (198703), Rumley Ann, Rumley, A, Gordon Lowe, Lowe, G   +30 more
core   +1 more source