Serum resistin is associated with C-reactive protein and LDL- cholesterol in type 2 diabetes and coronary artery disease in a Saudi population [PDF]
Aims Resistin is an adipocyte-derived factor implicated in obesity-associated type 2 diabetes (T2DM). This study examines the association between human serum resistin, T2DM and coronary heart disease.
N Al-Daghri +19 more
core +1 more source
Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? [PDF]
<p><b>Background:</b> Circulating inflammatory markers may more strongly relate to risk of fatal versus nonfatal cardiovascular disease (CVD) events, but robust prospective evidence is lacking.
Jukema, J.W. +14 more
core +1 more source
Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M. +46 more
core +1 more source
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +1 more source
Association between smoking and presence of Mycoplasma pneumoniae in circulation leukocytes
PRINCIPLES: The morbidity and mortality of infectious diseases due to smoking are not widely appreciated by physicians. However, cigarette smoking appears to be a major risk factor for respiratory tract and other systemic infections.
S Schumacher +6 more
doaj +1 more source
Relationship Among Circulating Inflammatory Proteins, Platelet Gene Expression, and Cardiovascular Risk [PDF]
Objective— Cardiovascular disease is a complex disorder influenced by interactions of genetic variants with environmental factors. However, there is no information from large community-based studies examining the relationship of circulating cell–specific RNA to inflammatory proteins.
McManus, David D +7 more
openaire +3 more sources
C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects [PDF]
Background Chronic low-grade inflammation, characterized by elevated plasma levels of C-reactive protein (CRP), has been inversely associated with dispositional optimism.
Craen, A.J.M. +19 more
core +1 more source
The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes:the MRC-ILA Heart Study [PDF]
AIMS: Acute coronary syndromes (ACSs) are driven by inflammation within coronary plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel-response to injury. ACS patients have raised serum markers of inflammation.
Greenwood, J.P. +29 more
core +1 more source
Peritoneal dialysis influences microRNA expression and pro-inflammatory response: results from a cross-sectional study [PDF]
Introduction: The investigation of circulating microRNAs (miRNAs) and inflammatory response associated with the different stages of chronic kidney disease (CKD) may reveal biomarkers of disease pathogenesis. Our goal was to identifying differences in the
Nara Aline Costa +14 more
doaj +1 more source
Objective To leverage large scale genetic association data to investigate the interplay between circulating cytokines and cardiometabolic traits, and thus identifying potential therapeutic targets.Design Bi-directional Mendelian randomisation study ...
Jian Huang +26 more
doaj +1 more source

