Results 61 to 70 of about 367,441 (304)

Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

Genome Medicine, 2020
Background The molecular factors which control circulating levels of inflammatory proteins are not well understood. Furthermore, association studies between molecular probes and human traits are often performed by linear model-based methods which may ...
Robert F. Hillary, Daniel Trejo-Banos, Athanasios Kousathanas, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Marion Patxot, Sven Erik Ojavee, Qian Zhang, David C. Liewald, Craig W. Ritchie, Kathryn L. Evans, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary, Matthew R. Robinson, Riccardo E. Marioni   +18 more
doaj   +1 more source

A4.4 Circulating Metastasis Promoting Protein S100A4 in Idiopathic Inflammatory Myopathies [PDF]

Annals of the Rheumatic Diseases, 2013
Background and Objectives Metastasis promoting protein S100A4 is involved in the pathogenesis of tumours and chronic autoimmune diseases such as rheumatoid arthritis (RA) and psoriasis. We recently described increased expression of S100A4 in inflamed muscle tissue in patients with idiopathic inflammatory myopathies (IIM).
L Pleštilová, O Pecha, H Mann, LA Cerezo, J Vencovský, L Šenolt   +5 more
openaire   +1 more source

Circulating inflammatory biomarkers and endometriosis lesion characteristics in the WisE consortium

npj Women's Health
Endometriosis is a chronic inflammatory condition requiring surgical or imaging visualization for definitive diagnosis. How endometriotic lesion characteristics relate to circulating inflammatory markers remains unclear.
Kathryn L. Terry, Amy Shafrir, Ashley Laliberte, Allison F. Vitonis, Kurtis Garbutt, Mary DePari, Christian Becker, Naoko Sasamoto, Krina T. Zondervan, Stacey A. Missmer   +9 more
doaj   +1 more source

Investigation of the association between circulating inflammatory proteins and encephalitis risk in Europeans by two-sample Mendelian randomization analysis

Frontiers in Neurology
BackgroundCytokines are powerful immune response factors that operate at inflammation sites and are also found in the blood. Nevertheless, research on encephalitis and these circulating inflammatory proteins is quite limited.MethodsThis study ...
Yanwei Liu, Xilong Wang, Qiang Zhao, Jun Wei, Shiqiang Yang   +4 more
doaj   +1 more source

Genetically Predicted Levels of Circulating Inflammatory Cytokines and the Risk and Age at Onset of Parkinson’s Disease: A Two-Sample Mendelian Randomization Study

Frontiers in Aging Neuroscience, 2022
Parkinson’s disease (PD) is widely considered to be a disabling neurodegenerative disorder, which has been ranked second worldwide just after Alzheimer’s disease.
Yating Zhao, Xiaoqian Zhang, Na Guo, Dandan Tian, Chenguang Zhang, Changqing Mu, Chen Han, Ruixia Zhu, Jian Zhang, Jian Zhang, Xu Liu   +10 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Genetics of Circulating Inflammatory Proteins and Iridocyclitis: An Exploratory Mendelian Randomization Study

Translational Vision Science & Technology
This study aimed to explore the potential causal relationship between genetically determined elevated levels of pro-inflammatory cytokines and iridocyclitis, including its subtypes: acute and subacute iridocyclitis (ASIR) and chronic iridocyclitis (CIR).A two-sample Mendelian randomization (MR) analysis was conducted using genome-wide association study
Liu, Huan, Li, Fuzhen, Wang, Feiyan, Hu, Ziqing, Du, Liping, Wei, Jing   +5 more
openaire   +2 more sources

Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women [PDF]

, 2009
AIMS: Secondhand smoke (SHS) exposure is associated with elevated CHD risks. Yet the pathways through which this may operate have not been investigated in epidemiologic studies with objective SHS exposure measures and a wide range of CHD risk factors ...
Lowe, G.D.O., Welsh, P, Lowe, GDO, Jefferis, B. J., Whincup, PH, Whincup, P.H., Ebrahim, S, Wannamethee, S.G., Jefferis, B.J., Lawlor, D. A., Rumley, A., McMeekin, L., Ebrahim, S., Whincup, P. H., Cook, D. G., Wannamethee, SG, Jefferis, BJ, Welsh, P., Lowe, GD, Feyerabend, C, Wannamethee, S. G., Lowe, G. D. O., Whincup, P., Feyerabend, C., Doig, M., Lawlor, DA, Cook, D.G., Carson, C., Doig, M, Rumley, A, Cook, DG, Carson, C, McMeekin, L, Lawlor, D.A.   +33 more
core   +1 more source

Profile of circulating levels of IL-1Ra, CXCL10/IP-10, CCL4/MIP-1β and CCL2/MCP-1 in dengue fever and parvovirosis

Memorias do Instituto Oswaldo Cruz, 2012
Dengue virus (DENV) and parvovirus B19 (B19V) infections are acute exanthematic febrile illnesses that are not easily differentiated on clinical grounds and affect the paediatric population.
Luzia Maria de-Oliveira-Pinto, Mariana Gandini, Laís Picinini Freitas, Marilda Mendonça Siqueira, Cíntia Ferreira Marinho, Sérgio Setúbal, Claire Fernandes Kubelka, Oswaldo Gonçalves Cruz, Solange Artimos de Oliveira   +8 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source