Results 51 to 60 of about 367,441 (304)

A genome-wide association study identifies protein quantitative trait loci (pQTLs) [PDF]

, 2008
There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts - cis effects, and ...
Marjo-Riitta Jarvelin, Simon-Sanchez, J, Hana Lango, Henley W, Greg Tranah, HURST A., Singleton, A, Murray, A, WEEDON M., McCarthy, Mark I, Rafferty I, Lango H, David Melzer, Rafferty, Ian, Singleton A, Bandinelli, S, Bennett, A, BRITTON A., Hurst, A, Newman, Anne B, van de Leemput J, Colin Dayan, GIBBS J., Paolisso, G, Lango, H, Dayan, Colin; id_orcid, Hurst A, Anne B Newman, Murray, Anna, FRAYLING T., Tranah, G, Panicker, V, Perry, John R. B., SHOLZ S., Frayling, Timothy M., Ferrucci, Luigi, Scholz, Sonja, Corsi AM, RICE N., Simon-Sanchez J, J Raphael Gibbs, Tranah G, Harris, Tamara, Jarvelin, Marjo-Riitta, Ruokonen A, Jarvelin, Marjo Riitta, Melzer, D, Paolisso G, Javier Simon-Sanchez, AREPALLI S., Amanda Bennett, Timothy M Frayling, Murray A, Scholz, S, Henley, William E., Hernandez D, Fulvio Lauretani, Hurst, Alison, Singleton, Andrew, RAFIQ S., Jarvelin MR, Rafiq S, McCarthy, MI, Perry, JR, Rafiq, S, Arepalli, S, van de Leemput, Joyce, PANICKER V., TRANAH G., Guralnik, J, Stevens K, Dayan, Colin M., Melzer, David, Rongling Li, Giuseppe Paolisso, Gibbs, J. Raphael, STEVENS K., Sajjad Rafiq, Corsi, Anna Maria, Perry JRB, Bennett A, Harris, T, Perry, John R.B., Bandinelli, Stefania, Nicole Washecka, Lauretani, Fulvio, Lango, Hana, Dena Hernandez, Harris T, Scholz S, McCarthy, Mark I., Frayling, Timothy M, William Henley, HARRIS T., Guralnik J, Stevens, K, Panicker, Vijay, Jack Guralnik, Li, R, DAYAN C., McCarthy MI, Rice N, Weedon, Michael N., Sampath Arepalli, Dayan C, Guralnik, Jack, Lauretani, F, John R B Perry, Melzer D, Dayan, C, Newman, Anne B., Lauretani F, RAFFERTY I., Britton A, Newman AB, Sonja Scholz, Angela Britton, HERNANDEZ D., Frayling TM, Corsi, Anna-Maria, Britton, A, Washecka, Nicole, Andrew Singleton, Ferrucci, L, Tamara Harris, LANGO H., Gibbs, JR, BENNET A., Perry, JRB, Dayan, Colin Mark, Michael N Weedon, Weedon, Michael N, Luigi Ferrucci, Bennett, Amanda, Neil Rice, Rice, N, Anna-Maria Corsi, BANDINELLI S., Washecka, N, Henley, William, Ruokonen, Aimo, Henley, W, Gibbs JR, SIMON SANCHEZ J., Kara Stevens, Arepalli, Sampath, Stevens, Kara, Joyce van de Leemput, MELZER D., Weedon MN, Frayling, TM, Panicker V, SINGLETON A., Weedon, MN, Dayan, Colin, Jarvelin, MR, Anna Murray, Arepalli S, Ferrucci L, FERRUCCI L., Rice, Neil, Li, Rongling, Tranah, Greg, Washecka N, HENLEY W., MCCARTHY M., Perry, John RB, Ruokonen, A, JARVELIN M., Li RL, VAN DE LEEMPUT J., Rafiq, Sajjad, PERRY J., Hernandez, Dena, WASHECKA N., Mark I McCarthy, Vijay Panicker, Ian Rafferty, MURRAY A., LI R., Newman, AB, Bandinelli S, NEWMAN A., Gibbs, J Raphael, Paolisso, Giuseppe, GURALNIK J., Hernandez, D, CORSI A., Van De Leemput, J, Simon-Sanchez, Javier, Stefania Bandinelli, Alison Hurst, RUOKONEN A., Corsi, AM, Britton, Angela, Rafferty, I, Aimo Ruokonen   +196 more
core   +1 more source

Expression of Heat Shock Protein 70 Gene and Its Correlation with Inflammatory Markers in Essential Hypertension. [PDF]

PLoS ONE, 2016
OBJECTIVES:Hypertension is characterized by systemic high blood pressure and is the most common and important risk factor for the development of cardiovascular diseases.
Kamna Srivastava, Rajiv Narang, Jagriti Bhatia, Daman Saluja   +3 more
doaj   +1 more source

The Effect of Circulating Inflammatory Proteins on Endometriosis: A Mendelian Randomization Study

ImmunoTargets and Therapy
Endometriosis is a complex gynecological condition in which endometrial fragments are implanted outside the uterus, causing pain and infertility. Although immune mediators play a vital role in endometriosis, their exact etiology remains elusive. Using Mendelian randomization (MR), this study aimed to assess the causal relationship between inflammatory ...
Wei,Yunfang, Zhao,Xianlei, Li,Linxia
openaire   +4 more sources

Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss [PDF]

, 2001
The association between hypoalbuminemia and poor prognosis in patients with cancer is well recognized. However, the factors that contribute to the fall in albumin concentrations are not well understood.
Watson, W.S., O'Gorman, P., Preston, T., McMillan, D.C., Scott, H.R., McArdle, C.S.   +5 more
core   +1 more source

Circulating inflammatory proteins and osteomyelitis: A bidirectional Mendelian randomization and colocalization analysis

Medicine
Circulating inflammatory proteins (CIPs) have been implicated in the progression of osteomyelitis (OM); however, whether these proteins play a causal role or are merely a consequence remains unclear. This study aimed to assess the causal relationships between CIPs and OM using a bidirectional 2-sample Mendelian randomization (MR) approach.
Tianxuan Feng, Peisheng Chen, Fengfei Lin   +2 more
openaire   +2 more sources

Ethnic variation in inflammatory profile in tuberculosis [PDF]

, 2013
Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine secretion when cultured with human macrophages in vitro.
Bothamley, GH, Baker Lucy V., Nikolayevskyy, V, Barker, Richard D., Adrian R. Martineau (136644), Heather J Milburn, Drobniewski, Francis A., Nuamah, RA, Martineau, AR, Timms Peter M., Francis A. Drobniewski (349928), Coussens, Anna K., Griffiths, CJ, Vladyslav Nikolayevskyy, Drobniewski, FA, Bhaw-Rosun, L, Rosamond A. Nuamah (430904), Kamrul Islam (430894), Coussens Anna K., Francis A Drobniewski, Milburn, HJ, Davidson Robert N., Nuamah Rosamond A., Alleyna P Claxton, Charles A Mein, Yasmeen Hanifa, Yasmeen Hanifa (430893), Drobniewski Francis A., Elkington, Paul T., Graham H. Bothamley (430896), Claxton Alleyna P., Graham H Bothamley, Elkington Paul T., Peter M. Timms (430895), Anna K. Coussens (430892), Davidson, Robert N., Vladyslav Nikolayevskyy (349919), Bhaw-Rosun Leena, Milburn, Heather, Martineau, Adrian R., Paul T. Elkington (364501), Packe, Geoffrey E., Mein, Charles A., Young, Douglas B., Geoffrey E Packe, Martineau Adrian R., Islam, Kamrul, Packe, GE, Mathina Darmalingam, Anna K Coussens, Robert N Davidson, Mathina Darmalingam (430899), Timms, Peter M., Rosamond A Nuamah, Hanifa, Yasmeen, Elkington, PT, Lucy V. Baker (430901), Nikolayevskyy, Vladyslav, Bothamley, Graham H., Richard D. Barker (430902), Milburn, Heather J., Leena Bhaw-Rosun (430903), Robert J Wilkinson, Baker, Lucy V., Darmalingam, M, Wilkinson, Robert J., Christopher J Griffiths, Bothamley Graham H., Robert J. Wilkinson (130050), Hanifa Yasmeen, Claxton, Alleyna P., Kamrul Islam, Darmalingam Mathina, Barker, RD, Peter M Timms, Wilkinson Robert J., Griffiths Christopher J., Islam Kamrul, Nuamah, Rosamond A., Hanifa, Y, Packe Geoffrey E., Barker Richard D., Claxton, AP, Alleyna P. Claxton (430897), Robert N. Davidson (364270), Coussens, AK, Timms, PM, Paul T Elkington, Christopher J. Griffiths (430905), Leena Bhaw-Rosun, Davidson, RN, Milburn Heather J., Griffiths, Christopher J., Lucy V Baker, Geoffrey E. Packe (430898), Richard D Barker, Darmalingam, Mathina, Nikolayevskyy Vladyslav, Heather J. Milburn (430900), Mein, CA, Charles A. Mein (46734), Baker, LV, Wilkinson, RJ, Adrian R Martineau, Mein Charles A., Bhaw-Rosun, Leena, Islam, K   +106 more
core   +1 more source

Dynamics of hepatic gene expression and serum cytokine profiles in single and double-hit burn and sepsis animal models

Data in Brief, 2015
We simulate the pathophysiology of severe burn trauma and burn-induced sepsis, using rat models of experimental burn injury and cecal ligation and puncture (CLP) either individually (singe-hit model) or in combination (double-hit model). The experimental
Rohit Rao, Mehmet A. Orman, Francois Berthiaume, Ioannis P. Androulakis   +3 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]

, 2006
Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
Wagner, Thomas, Reynders, Veerle, Veerle Reynders, Stefan Loitsch, Joachim Bargon, Reynders Veerle, Thomas Wagner, Steinhauer, Constanze, Bargon Joachim, Steinhilber Dieter, Bargon, Joachim, Loitsch Stefan, Dieter Steinhilber, Constanze Steinhauer, Loitsch, Stefan Marcel, Wagner Thomas, Steinhauer Constanze, Steinhilber, Dieter   +17 more
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source