Results 31 to 40 of about 367,441 (304)

Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus

Journal of the Association for Research in Otolaryngology, 2023
Abstract Background and Objective Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins.
Christopher R. Cederroth, Mun-Gwan Hong, Maxim B. Freydin, Niklas K. Edvall, Natalia Trpchevska, Carlotta Jarach, Winfried Schlee, Jochen M. Schwenk, Jose-Antonio Lopez-Escamez, Silvano Gallus, Barbara Canlon, Jan Bulla, Frances M. K. Williams   +12 more
openaire   +5 more sources

Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]

, 2011
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Jukema, J.W., Trompet, S., Sattar, N., David J. Stott, Jukema, J. Wouter, Heather M. Murray, Ian Ford, Ford, I., Welsh, Paul, Anton J.M. de Craen, McInnes, Iain B., Trompet, Stella, Paul Welsh, J. Wouter Jukema, Westendorp, Rudi G.J., McInnes, I.B., Welsh, P., Westendorp, R.G.J., Packard, C.J., Murray, H.M., Craen, A.J.M. de, de Craen, Anton J.M., Rudi G.J. Westendorp, Sattar, Naveed, Stella Trompet, Stott, David J., Naveed Sattar, Ford, Ian, Chris J. Packard, Murray, Heather M., PROSPER Study Grp, Packard, Chris J., Iain B. McInnes, Stott, D.J.   +33 more
core   +1 more source

A tryptophan metabolite prevents depletion of circulating endothelial progenitor cells in systemic low-grade inflammation

Frontiers in Immunology, 2023
BackgroundChronic systemic inflammation reduces the bioavailability of circulating endothelial progenitor cells (EPCs). Indoleamine 2,3-dioxygenase 1 (IDO1), a key enzyme of immune tolerance catalyzing the initial step of tryptophan degradation along the
Massimo R. Mannarino, Vanessa Bianconi, Giulia Scalisi, Luca Franceschini, Giorgia Manni, Alessia Cucci, Francesco Bagaglia, Giulia Mencarelli, Francesco Giglioni, Doriana Ricciuti, Filippo Figorilli, Benedetta Pieroni, Elena Cosentini, Eleonora Padiglioni, Cecilia Colangelo, Dietmar Fuchs, Paolo Puccetti, Antonia Follenzi, Matteo Pirro, Marco Gargaro, Francesca Fallarino   +20 more
doaj   +1 more source

Circulating PAMM, a novel antioxidant and anti-inflammatory protein, is elevated in acute SCI [PDF]

Journal of Translational Medicine, 2020
Abstract Background Peroxiredoxin activated in M-CSF stimulated monocytes (PAMM) is a novel protein produced by adipocytes with putative redox regulatory and anti-inflammatory properties. Because acute spinal cord injury (SCI) is associated with oxidative stress and neuroinflammation and because PAMM can be detected in systemic circulation, we ...
Leslie R. Morse, Nguyen Nguyen, Yan Xu, Prakash Jha, Ricardo A. Battaglino   +4 more
openaire   +3 more sources

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects. [PDF]

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

Impact of Gingivitis on Circulating Neutrophil Reactivity and Gingival Crevicular Fluid Inflammatory Proteins

International Journal of Environmental Research and Public Health, 2022
Gingivitis is an extremely common oral inflammatory condition and can be induced in humans using an acute 21-day experimental gingivitis model. Neutrophils are known to be highly prevalent in the gingival crevice during gingival inflammation; however, the effect of gingivitis and the associated biofilm on peripheral blood neutrophils (PBN) is not well ...
Helen M. Roberts, Zehra Yonel, Alpdogan Kantarci, Melissa M. Grant, Iain L. C. Chapple   +4 more
openaire   +2 more sources

Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke [PDF]

, 2008
BACKGROUND: Tumour necrosis factor alpha (TNFα) is a pro-inflammatory cytokine implicated in atherosclerotic plaque formation. We investigated whether circulating TNFα is prospectively associated with myocardial infarction (MI) or stroke in the older ...
Welsh, P, Lowe, GDO, Wannamethee, S. Goya, Whincup, PH, Welsh, PI, Thomson, Andrew G., Ebrahim, S, Lowe, Gordon DO, Carson, Claire, Lowe, Gordon D.O., Welsh, Paul, Lennon, Lucy T, Thomson, Andrew G, Thomson, AJ, Ebrahim, Shah, Wannamethee, SG, Thomson, AH, Jefferis, Barbara J, Lennon, Lucy T., Thomson, AG, Jefferis, BJ, Lowe, G.D., Lowe, GD, Whincup, Peter H, Rumley, Ann, Wannamethee, S Goya, Jefferis, Barbara J., Rumley, A, Lennon, LT, Carson, C, Whincup, Peter H.   +30 more
core   +1 more source

The correlation of circulating miR-29b and inflammatory markers with albuminuria in hypertensive patients

Clinical and Experimental Hypertension, 2020
Aims Circulating miR-29b and inflammatory process play a vital role in hypertension and hypertensive nephropathy. The aim of the present study was to investigate the association of circulating miR-29b and inflammatory markers with albuminuria and assess ...
Cheng Huang, Yu-Qing Huang
doaj   +1 more source

Circulating heat shock protein 60 levels are elevated in HIV patients and are reduced by anti-retroviral therapy. [PDF]

PLoS ONE, 2012
Circulating heat shock protein 60 (Hsp60) and heat shock protein 10 (Hsp10) have been associated with pro- and anti-inflammatory activity, respectively. To determine whether these heat shock proteins might be associated with the immune activation seen in
Itaru Anraku, Reena Rajasuriar, Caroline Dobbin, Richard Brown, Sharon R Lewin, Andreas Suhrbier   +5 more
doaj   +1 more source

Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study [PDF]

, 2005
BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis.
Mandal, K, Georg Wick, Mayr, M; id_orcid, Willeit, J, Xu, Q B, Qingzhong Xiao, Kiechl, S, Friedrich Oberhollenzer, Mayr, M, XIAO, Q, Georg Schett, Stefan Kiechl, Qingbo Xu, Wick, G, Johann Willeit, Kaushik Mandal, Oberhollenzer, F, Schett, G, Xiao, Q Z, Manuel Mayr, XU, Q   +20 more
core   +1 more source