Results 81 to 90 of about 115,123 (247)

Current trends of HIV recombination worldwide

Infectious Disease Reports, 2013
One of the major characteristics of HIV-1 is its high genetic variability and extensive heterogeneity. This characteristic is due to its molecular traits, which in turn allows it to vary, recombine, and diversify at a high frequency.
Katherine A. Lau, Justin J.L. Wong
doaj   +1 more source

Consistency of spatial dynamics of HIV-1 and HCV among HIV-1/HCV coinfected drug users in China

BMC Infectious Diseases, 2021
Background As the transmission routes of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) are similar, previous studies based on separate research on HIV-1 and HCV assumed a similar transmission pattern.
Yu Wang, Xin Chen, Mei Ye, Wei Pang, Chiyu Zhang, Si-Dong Xiong, Yong-Tang Zheng   +6 more
doaj   +1 more source

Antibody and B cell responses to Plasmodium sporozoites [PDF]

, 2014
Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria.
Cockburn, Ian A., Dups, Johanna N., Pepper, Marion   +2 more
core   +2 more sources

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Characterization of recombinant human plasma lecithin: cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

Journal of Lipid Research, 1998
The major N-linked carbohydrate structures were determined for recombinant human plasma lecithin:cholesterol acyltransferase (LCAT). The analysis of the structure of oligosaccharides by fast atom bombardment mass spectrometry (FAB-MS) and linkage ...
Andras G. Lacko, Andrew J. Reason, Colin Nuckolls, Bhalchandra J. Kudchodkar, Maya P. Nair, Geetha Sundarrajan, P. Haydn Pritchard, Howard R. Morris, Anne Dell   +8 more
doaj   +1 more source

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

Advanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen, Daniil Astapov, Nur Alia Oktaviani, Mami Goto, Keiji Numata, A. Sesilja Aranko   +5 more
wiley   +1 more source

A new homeostatic model of the T cell system

, 2010
Our main tenet argues that the primary role of positive thymic selection and the resulting T cell population is the maintenance of a homeostatic equilibrium with self MHC-self peptide complexes.
Bakacs, Tibor, Szabados, Tamas
core   +1 more source

Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity

Advanced Functional Materials, EarlyView.
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen, Zheyuan Miao, Gary Tom, Austin H. Cheng, Elizaveta Gusarova, Benjamen Zondag, Tianyi Wu, Dianoosh Kalhori, Boris Hinz, Milad Abolhasani, Alán Aspuru‐Guzik, Eugenia Kumacheva   +11 more
wiley   +1 more source

C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro [PDF]

, 2015
Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified.
Bianchi, Franca, Cotugno, Maria, DI CASTRO, SARA, FRATI, GIACOMO, MARCHITTI, Simona, RUBATTU, Speranza Donatella, SCARPINO, Stefania, SCIARRETTA, SEBASTIANO, Stanzione, Rosita, VOLPE, Massimo   +9 more
core   +1 more source

Coating Artificial Spider Silk Fiber with Magnetic FeCo: An Effective Strategy for Creating a Flexible Magneto‐Responsive Material

Advanced Functional Materials, EarlyView.
An original method is presented for producing artificial spider silk fibers with magnetic and magnetomechanical responsiveness, which consists in coating them with a nanometer‐thick layer of FeCo alloy by sputtering deposition. The challenge of combining organic materials and inorganic magnetic nanostructures is addressed, thus taking a step forward ...
Filippo Lanaro, Federico Spizzo, Gabriele Greco, Benjamin Schmuck, Anna Rising, Lucia Del Bianco   +5 more
wiley   +1 more source