Results 61 to 70 of about 52,233 (242)

Correction: Recombination Pattern Reanalysis of Some HIV-1 Circulating Recombination Forms Suggest the Necessity and Difficulty of Revision

PLOS ONE, 2016
[This corrects the article DOI: 10.1371/journal.pone.0107349.].
Lei Jia, Lin Li, Hanping Li, Siyang Liu, Xiaolin Wang, Zuoyi Bao, Tianyi Li, Daomin Zhuang, Yongjian Liu, Jingyun Li, PLOS ONE Editors   +10 more
openaire   +4 more sources

Cerebrospinal fluid viral load and intrathecal immune activation in individuals infected with different HIV-1 genetic subtypes. [PDF]

PLoS ONE, 2008
HIV-1 exhibits a high degree of genetic diversity and is presently divided into 3 distinct HIV-1 genetic groups designated major (M), non-M/non-O (N) and outlier (O).
Sahra Abdulle, Lars Hagberg, Bo Svennerholm, Dietmar Fuchs, Magnus Gisslén   +4 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Genetic characterization and recombinant history of a novel HIV-1 circulating recombinant form (CRF101_01B) identified in Yunnan, China

Infection, Genetics and Evolution, 2019
The high frequency of multiple HIV-1 recombinant events among the B, C and CRF01_AE were constantly occurring in Yunnan China. Here, we characterized a novel HIV-1 circulating recombinant form (CRF) consisting of CRF01_AE and subtype B (CRF101_01B) from three epidemiologically unlinked individuals. Phylogenetic analysis based on near full length genome
Chunyue Zhang, Yue Feng, Li Gao, Mi Zhang, Jing Miao, Xingqi Dong, Xueshan Xia   +6 more
openaire   +2 more sources

Genome Sequence of a Novel HIV-1 Circulating Recombinant Form 54_01B from Malaysia [PDF]

Journal of Virology, 2012
ABSTRACT We report here the first novel HIV-1 circulating recombinant form (CRF) 54_01B (CRF54_01B) isolated from three epidemiologically unlinked subjects of different risk groups in Malaysia. These recently sampled recombinants showed a complex genome organization composed of parental subtype B′ and CRF01_AE, with identical ...
Kim Tien, Ng, Lai Yee, Ong, Yutaka, Takebe, Adeeba, Kamarulzaman, Kok Keng, Tee   +4 more
openaire   +2 more sources

Assessing subtypes and drug resistance mutations among HIV-1 infected children who failed antiretroviral therapy in Kelantan, Malaysia

Brazilian Journal of Infectious Diseases, 2012
Antiretroviral (ARV) therapy has dramatically reduced morbidity and mortality in human immunodeficiency virus 1 (HIV-1) infected children. However, development of ARV resistance in these children is a major public health problem due to lack of ...
Suharni Mohamad, Zakuan Zainy Deris, Nik Khairulddin Yusoff, Tg Ahmad Akram Tg Mohd Ariffin, Rafidah Hanim Shueb   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Identification of a Novel HIV-1 Circulating Recombinant Form (CRF62_BC) in Western Yunnan of China [PDF]

AIDS Research and Human Retroviruses, 2014
We report here a novel HIV-1 circulating recombinant form (CRF62_BC) that was isolated from three epidemiologically unlinked individuals [one from an injecting drug user (IDU); two from heterosexuals] in Dehong prefecture of western Yunnan province.
Huamian, Wei, Jenny, His, Yi, Feng, Hui, Xing, Xiang, He, Lingjie, Liao, Song, Duan, Chuanyi, Ning, Nidan, Wang, Yutaka, Takebe, Yiming, Shao   +10 more
openaire   +2 more sources

Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon

Virology Journal, 2011
Background The HIV epidemic in Cameroon is characterized by a high degree of viral genetic diversity with circulating recombinant forms (CRFs) being predominant.
Nyambi Phillipe, Lee Sherwin, Tang Shixing, Wood Owen, Zhao Jiangqin, Ragupathy Viswanath, Hewlett Indira   +6 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source