Results 191 to 200 of about 6,088,596 (303)

Longitudinal monitoring of circulating tumor cell phenotypic conversion as a predictor of late recurrence in breast cancer: a prospective feasibility study using the GenoCTC platform. [PDF]

Front Oncol
Chelakkot C, Chelakkot VS, Shin H, Cho C, Park J, Choi J, Hong D, Lee HS, Shin YK.   +8 more
europepmc   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

Advanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang, Ying‐Chang Lu, Yu‐Ming Chang, Yen‐Hui Chan, Hong‐Yu Yan, Yi‐Shan Lee, Pei‐Hsuan Lin, Cheng‐Yu Hsieh, Chuan‐Jen Hsu, Tien‐Chen Liu, Hsien‐Yeh Chen, Chen‐Chi Wu   +11 more
wiley   +1 more source

AI-integrated multi-omics platform to revolutionize anti-metastatic therapy development through circulating tumor cell profiling: SCRUM-MONSTAR-CTC. [PDF]

Int J Clin Oncol
Hashimoto T, Shibuki T, Fujisawa T, Boku S, Kikuchi M, Shimizu A, Murakami T, Sakamoto Y, Miki I, Iida N, Kurano H, Yamashita R, Masuda J, Matsuda K, Yuda J, Yajima S, Kobayashi S, Liu Z, Amisaki M, Imai M, Nakamura Y, Bando H, Kim H, Gee HY, Lee HS, Park HW, Yoshino T.   +26 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Clinical Significance for Risk Stratification of Papillary Thyroid Cancer by TUMORFISHER Circulating Tumor Cell Technique. [PDF]

Clin Cancer Res
Jiang L, Li X, Ma T, Zeng P, Tan Z, Zheng C, Xu J, Zhang L, Guo Y, Liang J, Pan Y, Teng W, Tao Z, He J, Yu H, Wang J, Hu Z, Ge M.   +17 more
europepmc   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Erratum: Developing a prognostic risk model based on circulating tumor cell genes to predict prognosis and provide potential therapeutic strategies in colorectal cancer. [PDF]

Transl Cancer Res
Editorial Office.
europepmc   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review). [PDF]

Oncol Rep
Zhang L, Yuan Y, Deng Y, Wang L, Chen F.
europepmc   +1 more source