Results 201 to 210 of about 2,068,901 (353)
Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods
We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang +9 morewiley +1 more sourceSupplementary Methods from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
, 2023 Ellen Heitzer, Martina Auer, Christin Gasch, Martin Pichler, Peter Ulz, Eva Maria Hoffmann, Sigurd Lax, Julie Waldispuehl‐Geigl, Oliver Mauermann, Carolin Lackner, Gerald Höfler, Florian Eisner, Heinz Sill, Hellmut Samonigg, Klaus Pantel, Sabine Riethdorf, Thomas Bauernhofer, Jochen B. Geigl, Michael R. Speicher +18 moreopenalex +1 more sourcePulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
Nature Medicine, 2019 Francesca Chemi, D. Rothwell, N. Mcgranahan, Sakshi Gulati, C. Abbosh, S. Pearce, Cong Zhou, G. Wilson, M. Jamal-Hanjani, Nicolai J. Birkbak, J. Pierce, Chang Sik Kim, Saba Ferdous, D. Burt, Daniel Slane-Tan, F. Gomes, D. Moore, R. Shah, M. Al Bakir, C. Hiley, S. Veeriah, Y. Summers, P. Crosbie, S. Ward, B. Mesquita, M. Dynowski, D. Biswas, J. Tugwood, F. Blackhall, Crispin J. Miller, A. Hackshaw, G. Brady, C. Swanton, C. Dive, Charles Mariam Jonathan Jackie Dominic G. Caroline Ged Fra Swanton Jamal-Hanjani Tugwood Pierce Rothwell Dive, C. Swanton, C. Dive, G. Brady, Maise Al Bakir, D. Biswas, Y. Ngai, A. Sharp, Cristina Rodrigues, O. Pressey, Sean Smith, N. Gower, H. Dhanda, E. Kilgour, L. Priest, M. Krebs, M. Carter, C. Lindsay, T. Watkins, R. Rosenthal, M. Escudero, A. Stewart, A. Rowan, J. Goldman, P. van Loo, R. Stone, Tamara Denner, E. Nye, E. Lim, S. Boeing, M. Greco, K. Litchfield, J. Nicod, C. Puttick, Katey S. S. Enfield, Emma C. Colliver, B. Campbell, Yin Wu, M. Skrzypski, R. Hynds, A. Georgiou, M. W. Sunderland, J. Reading, S. Quezada, K. Peggs, T. Marafioti, J. Hartley, Pat Gorman, H. Lowe, L. Ensell, V. Spanswick, Angeliki Karamani, Maryam Razaq, Stephan Beck, A. Huebner, M. Dietzen, C. Naceur-Lombardelli, M. Akther, Haoran Zhai, Nnennaya Kannu, Elizabeth Manzano, S. Bola, E. Ghorani, M. R. de Massy, Elena Hoxha, E. Hatipoglu, Stephanie Ogwuru, B. Chain, R. Califano, Paul Taylor, P. Krysiak, K. Rammohan, E. Fontaine, R. Booton, M. Evison, Stuart Moss, Juliette Novasio, L. Joseph, P. Bishop, A. Chaturvedi, H. Doran, F. Granato, Vijay Joshi, E. Smith, A. Montero, Gillian Price, S. Dubois-Marshall, K. Kerr, Shirley Palmer, Heather Cheyne, Joy Miller, K. Buchan, M. Chetty, Mohammed Khalil, V. Ezhil, V. Prakash, G. Anand, Sajid Khan, K. Lau, M. Sheaff, Peter D. Schmid, L. Lim, J. Conibear, R. Schwarz, J. Le Quesne, Joan Riley, L. Primrose, L. Martinson, N. Carey, J. Shaw, D. Fennell, A. Nakas, S. Rathinam, Louise Nelson, K. Ryanna, Mohamad Tuffail, A. Bajaj, J. Brožík, Fiona Morgan, M. Kornaszewska, R. Attanoos, Haydn Adams, H. Davies, Z. Szallasi, R. Salgado, I. Csabai, M. Dióssy, H. Aerts, A. Kirk, M. Asif, J. Butler, Rocco Bilanca, N. Kostoulas, M. Mackenzie, M. Wilcox, S. Busacca, A. Dawson, Mark R. Lovett, M. Shackcloth, Sarah L. Feeney, Julius Asante-Siaw, J. Gosney, Angela E. Leek, Nicola Totten, Jack Davies Hodgkinson, Rachael Waddington, J. Rogan, K. Moore, W. Monteiro, H. Marshall, K. Blyth, C. Dick, A. Kidd, Eric Lim, Paulo De Sousa, S. Jordan, A. Rice, H. Raubenheimer, H. Bhayani, Morag Hamilton, L. Ambrose, A. Devaraj, Hema Chavan, S. Begum, A. Mani, Daniel Kaniu, Mpho Malima, S. Booth, A. Nicholson, Nádia Fernandes, Jessica E. Wallen, P. Shah, S. Danson, J. Bury, J. Edwards, Jennifer Hill, S. Matthews, Yota Kitsanta, J. Rao, S. Tenconi, L. Socci, K. Suvarna, F. Kibutu, P. Fisher, R. Young, Joanne Barker, Fiona G. Taylor, K. Lloyd, T. Light, T. Horey, D. Papadatos-Pastos, P. Russell, S. Lock, Kayleigh Gilbert, David S. Lawrence, M. Hayward, N. Panagiotopoulos, Robert S George, D. Patrini, M. Falzon, E. Borg, Reena Khiroya, Asia Ahmed, Magali N. Taylor, Junaid Choudhary, P. Shaw, S. Janes, Martin D. Forster, T. Ahmad, S. Lee, Javier Herrero, D. Carnell, R. Mendes, J. George, N. Navani, D. Papadatos-Pastos, M. Scarci, E. Bertoja, R. Stephens, Emilie Martinoni Hoogenboom, James W. Holding, S. Bandula, B. Naidu, G. Langman, Andrew Robinson, H. Bancroft, A. Kerr, S. Kadiri, C. Ferris, G. Middleton, M. Djearaman, Akshay J. Patel, C. Ottensmeier, S. Chee, Benjamin Johnson, A. Alzetani, E. Shaw, Jason Lester +271 moresemanticscholar +1 more sourceUnraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou +10 morewiley +1 more sourceFunctional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen +8 morewiley +1 more sourceβ‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia +11 morewiley +1 more sourceDetection of circulating tumor cells in patients with lung cancer using a Rare Cell Sorter: a pilot study [PDF]
Kazuto Sugai, Tomoko Mori, Bilal Turan, Atsuko Furukawa, Yasuharu Sekine, Naohiro Kobayashi, Shinji Kikuchi, Yukinobu Goto, Hideo Ichimura, Taisuke Masuda, Fumihito Arai, Yukio Sato, Satoshi Matsusaka +12 moreopenalex +1 more source
