Results 301 to 310 of about 1,992,684 (401)

Challenges in circulating tumor cell detection by the CellSearch system

Molecular Oncology, 2016
K. Andree, G. van Dalum, L. Terstappen
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Label-Free Microfluidic Apheresis of Circulating Tumor Cell Clusters. [PDF]

Adv Sci (Weinh)
Zhan L, Edd J, Mishra A, Toner M.
europepmc   +1 more source

Proportion of circulating tumor cell clusters increases during cancer metastasis

Cytometry Part A, 2017
Yuanzhen Suo, Cheng-ying Xie, Xi Zhu, Zhichao Fan, Zhangru Yang, Hao He, Xunbin Wei   +6 more
semanticscholar   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Establishing a Highly Accurate Circulating Tumor Cell Image Recognition System for Human Lung Cancer by Pre-Training on Lung Cancer Cell Lines. [PDF]

Cancers (Basel)
Matsumiya H, Terabayashi K, Kishi Y, Yoshino Y, Mori M, Kanayama M, Oyama R, Nemoto Y, Nishizawa N, Honda Y, Kuwata T, Takenaka M, Chikaishi Y, Yoneda K, Kuroda K, Ohnaga T, Sasaki T, Tanaka F.   +17 more
europepmc   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Role of GPX3+ astrocytes in breast cancer brain metastasis activated by circulating tumor cell exosomes. [PDF]

NPJ Precis Oncol
Huang G, Xu G, Cao Q, Li S, Li H, Zhang X, Li X.   +6 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Total metabolic tumor volume, circulating tumor cells, cell-free DNA: distinct prognostic value in follicular lymphoma.

Blood Advances, 2018
M. Delfau-Larue, A. Van Der Gucht, J. Dupuis, J. Jais, I. Nel, A. Beldi-Ferchiou, S. Hamdane, I. Benmaad, G. Labouré, Benjamin Verret, C. Haioun, C. Copie-Bergman, A. Berriolo-Riedinger, P. Robert, R. Casasnovas, E. Itti   +15 more
semanticscholar   +1 more source