Results 181 to 190 of about 2,021,965 (393)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Optical nanomaterial-based detection of biomarkers in liquid biopsy

Journal of Hematology & Oncology
Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy, has been introduced as a new diagnostic/prognostic measure.
Young Jun Kim, Won-Yeop Rho, Seung-min Park, Bong-Hyun Jun   +3 more
doaj   +1 more source

Microphthalmia transcription factor as a molecular marker for circulating tumor cell detection in blood of melanoma patients. [PDF]

, 2006
Kazuo Koyanagi, Steven O’Day, René González, Karl D. Lewis, William A. Robinson, Thomas Amatruda, Christine Kuo, Hejing Wang, Robert Milford, Donald L. Morton, Dave S.�B. Hoon   +10 more
openalex   +1 more source

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

Science, 2013
Min Yu, A. Bardia, Ben S. Wittner, Shannon L. Stott, Malgorzata E. Smas, D. Ting, S. Isakoff, Jordan C. Ciciliano, Marissa N. Wells, Ajay M Shah, K. Concannon, M. C. Donaldson, L. Sequist, E. Brachtel, D. Sgroi, J. Baselga, Sridhar Ramaswamy, M. Toner, D. Haber, S. Maheswaran   +19 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Central nervous system relapse in patients with breast cancer is associated with advanced stages, with the presence of circulating occult tumor cells and with the HER2/neu status [PDF]

, 2006
John Souglakos, Lambros Vamvakas, Stella Apostolaki, Maria Perraki, Zacharenia Saridaki, Irine Kazakou, Athanasios Pallis, Charalambos Kouroussis, N. Androulakis, Kostas Kalbakis, G. Millaki, Dimitris Mavroudis, Vassilis Georgoulias   +12 more
openalex   +1 more source

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy.

Cancer Discovery, 2016
C. Alix-Panabières, K. Pantel
semanticscholar   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Circulating Tumor Cells in Perioperative Esophageal Cancer Patients: Quantitative Assay System and Potential Clinical Utility [PDF]

, 2007
Zhian Liu, Ming Jiang, Jianhua Zhao, Huangxian Ju   +3 more
openalex   +1 more source