Results 171 to 180 of about 5,339,936 (244)

Preoperative Mutational Analysis of Circulating Tumor Cells (CTCs) and Plasma-cfDNA Provides Complementary Information for Early Prediction of Relapse: A Pilot Study in Early-Stage Non-Small Cell Lung Cancer. [PDF]

Cancers (Basel), 2023
Markou AN, Londra D, Stergiopoulou D, Vamvakaris I, Potaris K, Pateras IS, Kotsakis A, Georgoulias V, Lianidou E.   +8 more
europepmc   +1 more source

A Droplet‐Microarray Platform for Multiplex Profiling of Breast Cancer Exosome Subtypes in Patients’ Blood Plasma Samples

Small, Volume 22, Issue 49, 1 September 2026.
This study presents a droplet‐microarray platform integrated with a DNase I‐assisted MoS2 FRET aptasensor for multiplexed profiling of breast cancer subtypes’ exosomes from patients’ plasma. By targeting HER2, MUC1, and CD44, the system enables sensitive detection and accurate discrimination of luminal A, HER2‐positive, and triple‐negative subtypes ...
Yi Liu, Ruolin Zhang, Jialei Song, Meng Xiao, Yue Meng, Zhiyang Li, Jingyu Shi, Yunyan Tai, Bing Gu, Mo Yang   +9 more
wiley   +1 more source

Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer

Communications Medicine
Background: Heterogeneous circulating tumor cells (CTCs) have been implicated in the formation of new metastases. However, circulating cells expressing both tumor and immune cell proteins are often dismissed as insignificant findings in CTC studies ...
Nikki Higa, Audrey Limb, Valerie Hennes, Andrés Rivera, Rafael Nevarez, Anand Kolatkar, Carol K. Tweed, Adam I. Riker, Young Lee, Lorraine Tafra, Jeremy G. Perkins, Craig D. Shriver, Peter Kuhn, James Hicks   +13 more
doaj   +1 more source

Preoperative High Level of Circulating Tumor Cells is an Independent Risk Factor for Central Lymph Node Metastasis in Papillary Thyroid Carcinoma with Maximum Lesion Diameter ≤1.0 cm [PDF]

Ming Yu, Jiaqin Deng, Yihua Gu, Yeqian Lai Department of Thyroid Surgery, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of ChinaCorrespondence: Ming Yu, Department of Thyroid Surgery, Meizhou People’s Hospital,
Lai Y, Yu M, Gu Y, Deng J
core  

Engineering the Electrochemiluminescence Microenvironment: Mechanistic Roles of Nanomaterials in Aptamer‐Based Sensors

Small Structures, Volume 7, Issue 9, September 2026.
This review highlights how nanomaterials have transformed electrochemiluminescence (ECL) aptasensors beyond their traditional role as supports. It examines their emerging roles as new ECL luminophores and active regulators of the ECL microenvironment within aptasensors.
Ana Díaz‐Fernández, Noemí de‐los‐Santos‐Álvarez, María Jesús Lobo‐Castañón   +2 more
wiley   +1 more source

Multigene Profiling of Circulating Tumor Cells (CTCs) for Prognostic Assessment in Treatment-Naïve Metastatic Hormone-Sensitive Prostate Cancer (mHSPC). [PDF]

Int J Mol Sci, 2021
Reichert ZR, Kasputis T, Nallandhighal S, Abusamra SM, Kasputis A, Haruray S, Wang Y, Williams S, Singhal U, Alva A, Cackowski FC, Caram MEV, Palmbos PL, Yentz SE, Smith DC, Alumkal JJ, Morgan TM.   +16 more
europepmc   +1 more source

Delayed Occurrence of Lung Cancer Leptomeningeal Metastasis and Era‐Associated Post‐LM Survival: A 14‐Year Single‐Center Cohort Study

Thoracic Cancer, Volume 17, Issue 17, September 2026.
In 201 cytology‐confirmed lung cancer LM cases, the modern era was associated with later LM diagnosis but no significant unadjusted improvement in post‐LM survival. Paired tissue‐CSF profiling identified actionable driver discordance in 8.75%, supporting CSF testing and improved CNS‐penetrant, molecularly matched therapies.
Xiaoxing Gao, Jie Gao, Qiuyue Ye, Chen Wei, Qing Zhou, Xiaoyan Liu, Minjiang Chen, Jing Zhao, Hanping Wang, Xiaoyan Si, Wei Zhong, Yan Xu, Mengzhao Wang   +12 more
wiley   +1 more source

TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications. [PDF]

Cancers (Basel), 2022
Papadaki MA, Monastirioti A, Apostolopoulou CA, Aggouraki D, Papadaki C, Michaelidou K, Vassilakopoulou M, Alexakou K, Mavroudis D, Agelaki S.   +9 more
europepmc   +1 more source

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, Volume 59, Issue 9, September 2026.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

Cytopathology, Volume 37, Issue 5, Page 438-448, September 2026.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati, V. Callegari, A. Ancora, M. Palmieri, B. Riccò, E. Cabitza, L. Trudu, K. Di Emidio, C. Chiavelli, A. Eccher, I. Mastrolia, V. Catani, S. Bettelli, G. Guaitoli, M. Dominici, F. Bertolini   +15 more
wiley   +1 more source