Results 61 to 70 of about 250,499 (303)

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

Dynamics and Statistics of Reorientations of Large-Scale Circulation in Turbulent Rotating Rayleigh-B\'{e}nard Convection

, 2019
We present a direct numerical simulation to investigate the dynamics and statistics of reorientations of large-scale circulation (LSC) in turbulent rotating Rayleigh-B\'{e}nard convection (RRBC) for air ($Pr=0.7$) contained in a cylindrical cell with ...
De, Arnab Kumar, Mishra, Pankaj Kumar, Vishnu, Venugopal T   +2 more
core   +1 more source

Direct numerical simulations of vortex rings at ReΓ = 7500 [PDF]

, 2007
We present direct numerical simulations of the turbulent decay of vortex rings with ReΓ = 7500. We analyse the vortex dynamics during the nonlinear stage of the instability along with the structure of the vortex wake during the turbulent stage.
Bergdorf, Michael, Koumoutsakos, Petros, Leonard, Anthony   +2 more
core   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Starting flow through nozzles with temporally variable exit diameter [PDF]

, 2005
Starting flow through a nozzle or orifice typically results in the transient formation of a leading vortex ring and trailing jet. Experiments are conducted to investigate the dynamics of this process in the case of a temporally variable nozzle exit ...
Dabiri, John O., Gharib, Morteza
core  

Unsteady forces on an accelerating plate and application to hovering insect flight [PDF]

, 2004
The aerodynamic forces on a flat plate accelerating from rest at fixed incidence in two-dimensional power-law flow are studied analytically and numerically.
Pullin, D. I., Wang, Z. Jane
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Study on the internal two-phase flow of the inverted-umbrella aerator

Advances in Mechanical Engineering, 2019
In order to reveal the gas–liquid two-phase flow pattern of inverted-umbrella aerator, the high-speed photography technology, particle image velocimetry, and Volume of Fluid model are employed to capture the free-surface dynamics and velocity ...
Liang Dong, Jiawei Liu, Houlin Liu, Cui Dai, Dmitry Vladimirovich Gradov   +4 more
doaj   +1 more source

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

Fluids and Barriers of the CNS, 2019
The fine balance between the secretion, composition, volume and turnover of cerebrospinal fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance can be disrupted.
Steven William Bothwell, Damir Janigro, Adjanie Patabendige   +2 more
doaj   +1 more source