Results 61 to 70 of about 245,968 (334)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Characteristics of Two-Dimensional Quantum Turbulence in a Compressible Superfluid [PDF]

, 2012
Under suitable forcing a fluid exhibits turbulence, with characteristics strongly affected by the fluid's confining geometry. Here we study two-dimensional quantum turbulence in a highly oblate Bose-Einstein condensate in an annular trap.
A. S. Bradley, A. N. Kolmogorov, B. P. Anderson, E. C. Samson, E. M. Wright, J. Sommeria, K. J. H. Law, L. P. Pitaevskii, M. J. Davis, M. Lesieur, P. G. Kevrekidis, R. Carretero-González, S. J. Rooney, T. W. Neely   +13 more
core   +2 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Emergence of decadal linkage between Western Australian coast and Western–central tropical Pacific

Nature Communications
The impact of interbasin linkage on the weather/climate and ecosystems is significantly broader and profounder than that of only appearing in an individual basin. Here, we reveal that a decadal linkage of sea surface temperature (SST) has emerged between
Yuewen Ding, Pengfei Lin, Hailong Liu, Bo Wu, Yuanlong Li, Lin Chen, Lei Zhang, Aixue Hu, Yiming Wang, Yiyun Yao, Bowen Zhao, Wenrong Bai, Weiqing Han   +12 more
doaj   +1 more source

Numerical Simulation Study of Seafloor Hydrothermal Circulation Based on HydrothermalFoam: A Case Study of the Wocan-1 Hydrothermal Field, Carlsberg Ridge, Indian Ocean

Journal of Marine Science and Engineering, 2023
Deep-sea hydrothermal circulation plays a pivotal role in the material and energy exchange in deep-sea environments, exerting significant influence on the evolution of seawater chemistry and global climate dynamics. Based on existing data and assumptions,
Haoyang Zeng, Peng Hu, Zhiguo He, Jinrong Yao, Zhiying Yang   +4 more
doaj   +1 more source

Unsteady forces on an accelerating plate and application to hovering insect flight [PDF]

, 2004
The aerodynamic forces on a flat plate accelerating from rest at fixed incidence in two-dimensional power-law flow are studied analytically and numerically.
Pullin, D. I., Wang, Z. Jane
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Coupling of lung tissue tethering force to fluid dynamics in the pulmonary circulation

International Journal for Numerical Methods in Biomedical Engineering, 2010
AbstractDynamic changes in lung volume during breathing and alteration of posture are both known to influence the distribution of perfusion within the lung. Here we couple computational models of pulmonary blood flow and parenchymal tissue mechanics to produce a novel flow model that predicts tissue deformation simultaneously with flow distributions at
Burrowes, K, Tawhai, M
openaire   +3 more sources

Delay of vortex ring pinchoff by an imposed bulk counterflow [PDF]

, 2004
The Kelvin–Benjamin variational principle has been previously used to predict that vortex ring pinchoff can be delayed if the energy of the leading vortex ring is decreased during formation and/or the energy delivered by the vortex generator is increased.
Dabiri, John O., Gharib, Morteza
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source