Results 61 to 70 of about 1,048,370 (263)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

CIS: v1.4.0

open access: yes, 2016
<p>The Community Intercomparison Suite (CIS) is an easy-to-use command-line tool which has been developed to allow the straightforward intercomparison of remote sensing, in-situ and model data.</p> <p>Developed by a professional ...
Nick Schutgens   +7 more
core   +1 more source

IONIC LIQUIDS FOR CAPTURE AND ELECTROCHEMICAL CONVERSION OF CO2 - CIS 2021 [PDF]

open access: yes, 2021
The exponential increase in the concentration of greenhouse gasses in the atmosphere is considered one of the most important reasons for climate change. Carbon Dioxide is the most significant anthropogenic gas that contributes to global warming.
María José Rubio   +5 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

cedadev/cis: v1.7.2

open access: yes, 2020
CIS 1.7.2 fixes We no-longer officially support Python 2.7. We won't yet explicitly remove Python 2.7 features but we no longer test against Python 2 and won't fix issues relating to it. Support for Pandas 1.
matt-kendall   +8 more
core   +1 more source

Aprovechamiento de escorias de fundición de empresas del sector azucarero en la obtención de matriz de un fundente aglomerado para recuperación de piezas del propio sector

open access: yesRevista Centro Azúcar, 2007
Se presenta el aprovechamiento de escorias de la producción de hierro en hornos de cubilote en empresas de la industria azucarera para la obtención de una matriz de un fundente para recuperación de piezas por arco sumergido en el propio sector.
Rubén Jerez Pereira   +3 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

CIS-7 Perspective on Trade with EU in the Context of EU Enlargement [PDF]

open access: yes
The paper analyses possible consequences of the EU enlargement on the EU – CIS-7 trade. It considers current situation in trade between two country groups, describes the factors limiting this trade, and discusses the opportunities for the trade ...
Roman Mogilevsky
core  

cis-eQTL in T2DM-relevant tissues.

open access: yes, 2018
The Venn diagram indicates the numbers of cis-eQTLs in pancreas, liver, adipose subcutaneous and skeletal muscle, and the numbers shared among these tissues.
Tom Hooimeijer (5058752)   +8 more
core   +1 more source

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