Results 71 to 80 of about 1,713,481 (307)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Facile Synthesis of Effcient and Selective Ruthenium Olefin Metathesis Catalysts with Sulfonate and Phosphate Ligands [PDF]
A series of novel, air-stable ruthenium NHC catalysts with sulfonate and phosphate anions have been prepared easily in one pot at high yields using commercially available precursors.
Grubbs, Robert H., Teo, Peili
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Se presenta el aprovechamiento de escorias de la producción de hierro en hornos de cubilote en empresas de la industria azucarera para la obtención de una matriz de un fundente para recuperación de piezas por arco sumergido en el propio sector.
Rubén Jerez Pereira +3 more
doaj
Armenia: an Uneasy Choice Between Russia's New Initiatives and the EU Eastern Partnership
The article studies the problems of foreign policy orientations of the Republic of Armenia, first of all those concerning "Russian" and "European" integration processes. Particularly, the main stages and peculiarities of Armenia's cooperation with the EU
M. Y. Vardazaryan
doaj +1 more source
Techno-economic indicators of renewable (solar and wind) and non-renewable energy sources are systematized, taking into account the interval of their uncertainty for the conditions of the countries of the Commonwealth of Independent States (CIS).
O. V. Marchenko, S. V. Solomin
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Unravelling the Correlation of Electronic Structure and Carrier Dynamics in CuInS\u3csub\u3e2\u3c/sub\u3e Nanoparticles [PDF]
In this work, we report the direct correlation of photoinduced carrier dynamics and electronic structure of CuInS2 (CIS) nanoparticles (NPs) using the combination of multiple spectroscopic techniques including steady-state X-ray absorption spectroscopy ...
Hu, Wenhui +7 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Photochemical studies of cis-[Ru(bpy)2(4-bzpy)(CO)](PF6)2 and cis-[Ru(bpy)2(4-bzpy)(Cl)](PF6): Blue light-induced nucleobase binding. [PDF]
The ruthenium(II) compounds cis-[Ru(bpy)2(4-bzpy)(CO)](PF6)2 (I) and cis-[Ru(bpy)2(4-bzpy)(Cl)](PF6) (II) (4-bzpy=4-benzoylpyridine, bpy=2,2'-bipyridine) were synthesized and characterized by spectroscopic and electrochemical techniques.
Carvalho, Edinilton M +7 more
core +4 more sources

