Results 71 to 80 of about 1,695,888 (310)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Armenia: an Uneasy Choice Between Russia's New Initiatives and the EU Eastern Partnership
The article studies the problems of foreign policy orientations of the Republic of Armenia, first of all those concerning "Russian" and "European" integration processes. Particularly, the main stages and peculiarities of Armenia's cooperation with the EU
M. Y. Vardazaryan
doaj +1 more source
Techno-economic indicators of renewable (solar and wind) and non-renewable energy sources are systematized, taking into account the interval of their uncertainty for the conditions of the countries of the Commonwealth of Independent States (CIS).
O. V. Marchenko, S. V. Solomin
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Quotients of CI-Groups are CI-Groups [PDF]
We show that a quotient group of a CI-group with respect to (di)graphs is a CI-group with respect to (di)graphs.
Dobson, Edward, Morris, Joy
openaire +4 more sources
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Se presenta el aprovechamiento de escorias de la producción de hierro en hornos de cubilote en empresas de la industria azucarera para la obtención de una matriz de un fundente para recuperación de piezas por arco sumergido en el propio sector.
Rubén Jerez Pereira +3 more
doaj
Submillimeter Spectrum of Formic Acid
We have measured new submillimeter-wave data around 600 GHz and around 1.1 THz for the 13C isotopologue of formic acid and for the two deuterium isotopomers; in each case for both the trans and cis rotamer.
Drouin, Brian J. +3 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Facile Synthesis of Effcient and Selective Ruthenium Olefin Metathesis Catalysts with Sulfonate and Phosphate Ligands [PDF]
A series of novel, air-stable ruthenium NHC catalysts with sulfonate and phosphate anions have been prepared easily in one pot at high yields using commercially available precursors.
Grubbs, Robert H., Teo, Peili
core +1 more source

