Results 211 to 220 of about 2,487,415 (296)

Reduced Exosomal miR-22 Promotes Cisplatin Resistance and Migration in Non-Small Cell Lung Cancer Cells Through MDM4 Upregulation. [PDF]

Onco Targets Ther
Wang P, Jiao J, Yu L, Zhao R.
europepmc   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

Polyphyllin I Orchestrates Autophagy to Reprogram the Tumour Immune Microenvironment and Abrogate Cisplatin Resistance in Non-Small Cell Lung Cancer. [PDF]

Clin Exp Pharmacol Physiol
Liu Z, Li Y, Li S, Wang Z, Zhao H, Ke K, Wan C, Shi X.   +7 more
europepmc   +1 more source

Cisplatin resistance

, 1995
openaire   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

HDAC2-Mediated SMAD7 Stabilisation Activates Wnt/β-Catenin Signalling to Drive DNA Damage Repair and Cisplatin Resistance in Ovarian Cancer. [PDF]

J Cell Mol Med
He Y, Wu M, Xu X, Zheng K, Zhou K.
europepmc   +1 more source

Dihydrotanshinone I Targets MIF to Inhibit GSK‐3β/β‐Catenin Axis‐Mediated Invasion and Metastasis in Gastric Cancer

Phytotherapy Research, EarlyView.
DHT directly binds to MIF and subsequently blunts AKT signaling, which restores the kinase activity of GSK‐3β. The reactivated GSK‐3β then promotes the phosphorylation (Ser33/37/Thr41) and proteasomal degradation of β‐catenin, thereby preventing its nuclear translocation and inhibiting the transcription of EMT‐related genes (e.g., Snail and Twist ...
Chuhang Wang, Xiaochen Ni, Yuyan Pan, Wei Fan, Jianing Guo, Kaiyuan Zhang, Mingsi Zhang, Linfeng Zheng, Yunhai Wei, Tao Jiang, Guangji Zhang   +10 more
wiley   +1 more source

YAP inactivation-mediated autophagy inhibition contributes to cisplatin resistance in ovarian cancer cells. [PDF]

J Ovarian Res
Nguyen NT, Hsieh MR, Nguyen HDH, Chimphlee W, Visitsattapongse S, Chiu WT.   +5 more
europepmc   +1 more source

Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer

Phytotherapy Research, EarlyView.
Dihydroartemisinin Engages NQO1 and Promotes Ferroptosis‐Related Oxidative Stress in Non‐Small Cell Lung Cancer. ABSTRACT Dihydroartemisinin (DHA), a bioactive derivative of Artemisia annua L. (AAL), has shown antitumor activity in several malignancies, including non‐small cell lung cancer (NSCLC).
Xiuli Guo, Gan Tao, Mini Zhang, Linzhi Han, Sisi Yan, Chunsheng Wang, Jianguo Zhang, Xiaowan Guo, Kehua Hu, Yan Gong, Qiuji Wu, Conghua Xie   +11 more
wiley   +1 more source