Results 101 to 110 of about 6,727 (271)

Unveiling citicoline's mechanisms and clinical relevance in the treatment of neuroinflammatory disorders

The FASEB Journal
Citicoline, a compound produced naturally in small amounts in the human body, assumes a pivotal role in phosphatidylcholine synthesis, a dynamic constituent of membranes of neurons.
S. Cavalu, Sameh Saber, Asmaa Ramadan, Elsayed A. Elmorsy, Rabab S. Hamad, M. A. Abdel-Reheim, Mahmoud E. Youssef   +6 more
semanticscholar   +1 more source

CEST effect of dimethyl sulfoxide at negative offset frequency

NMR in Biomedicine, Volume 37, Issue 12, December 2024.
DMSO, the common solvent, along with its several protic and aprotic analogs, exhibited CEST effects at the negative offset range of Z‐spectrum, from −1.4 to −3.8 ppm. The origin of the CEST effect could be magnetization transfer pathways involving solvent–water molecular interactions.
Haoyun Su, Lok Hin Law, Yang Liu, Jianpan Huang, Kannie W. Y. Chan   +4 more
wiley   +1 more source

Post-stroke cognitive impairment and treatment options

Медицинский совет, 2015
Cognitive impairment is a widespread serious complication of ischemic stroke requiring intensive medication treatment. Citicoline is a medicine with proven efficacy in ischemic stroke and vascular cognitive impairment. The article provides an overview of
A. N. Bogolepova
doaj   +1 more source

Dopamine and Citicoline-Co-Loaded Solid Lipid Nanoparticles as Multifunctional Nanomedicines for Parkinson’s Disease Treatment by Intranasal Administration

Pharmaceutics
This work aimed to evaluate the potential of the nanosystems constituted by dopamine (DA) and the antioxidant Citicoline (CIT) co-loaded in solid lipid nanoparticles (SLNs) for intranasal administration in the treatment of Parkinson disease (PD).
Stefano Castellani, G. N. Iaconisi, Francesca Tripaldi, Vito Porcelli, A. Trapani, Eugenia Messina, Lorenzo Guerra, C. Di Franco, G. Maruccio, A. G. Monteduro, F. Corbo, S. Di Gioia, Giuseppe Trapani, Massimo Conese   +13 more
semanticscholar   +1 more source

Citicoline Treatment Increases Retinal Dopamine Content in Rabbits

Ophthalmic Research, 2002
Citicoline (exogenous cytidine-5′-diphosphocholine) was reported to enhance dopaminergic neurotransmission in the brain. A few clinical studies showed beneficial effects of this drug on the function of the visual pathway in patients with glaucoma or amblyopia.
Robert, Rejdak, Jerzy, Toczołowski, Janusz, Solski, Dariusz, Duma, Paweł, Grieb   +4 more
openaire   +2 more sources

Application of Citicoline in Neurological Disorders: A Systematic Review [PDF]

, 2020
Patryk Jasielski, Faustyna Piędel, Mikołaj Piwek, Agata Rocka, Véronique Petit, Konrad Rejdak   +5 more
openalex   +1 more source

Neuroprotection by Cerebrolysin and Citicoline Through the Upregulation of Brain-Derived Neurotrophic Factor (BDNF) Expression in the Affected Neural Cells: A Preliminary Clue Obtained Through an In Vitro Study

Cureus
Objectives: Citicoline and cerebrolysin are two unique yet contentious medications because of inconsistencies in efficacy as well as the mystery surrounding their mode of action.
Anandan P, Santhanam Rengarajan, S. Venkatachalam, Sasikumar Pattabi, Sumathi Jones, P. K, Vani Krishna, Krishna Prasanth   +7 more
semanticscholar   +1 more source

Successful treatment with guanfacine in a long‐COVID case manifesting marked cognitive impairment

Neuropsychopharmacology Reports, Volume 44, Issue 3, Page 585-590, September 2024.
A patient with long‐COVID manifesting apparent cognitive impairment was successfully treated with guanfacine, a selective α2A‐adrenoceptor agonist. Guanfacine may be helpful in improving subjective and objective cognitive functioning together with frontotemporal brain activity in such patients.
Tsuyoshi Kondo, Riki Higa, Mariko Kuniba, Hotaka Shinzato, Yoshikazu Takaesu   +4 more
wiley   +1 more source

Citicoline for ischemic stroke: ICTUS trial

Неврология, нейропсихиатрия, психосоматика, 2012
The paper gives data available in the literature on the use of citicoline in an experimental model of ischemic stroke (IS) and in randomized multicenter placebo-controlled trials.
Vladimir Anatolyevich Parfenov
doaj   +1 more source

A Nutrient Combination that Can Affect Synapse Formation [PDF]

, 2014
Brain neurons form synapses throughout the life span. This process is initiated by neuronal depolarization, however the numbers of synapses thus formed depend on brain levels of three key nutrients—uridine, the omega-3 fatty acid DHA, and choline.
Wurtman, Richard Jay
core   +2 more sources