Results 51 to 60 of about 5,671,494 (392)
, 2013 Towns and cities existed throughout Africa’s past. However since the late twentieth century Africans are witnessing a historically unprecedented transition from living mainly in rural areas to residing in cities.
Meier Zu Selhausen, Felix
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Journal of Urban History, 2020 To be fully human in the Greco-Roman world was to be a member of a city. This is unsurprising as cities were the building blocks of Greek and Roman culture and society. The urban landscape of post-Roman Western Europe looked dramatically different, with smaller, less economically diverse cities which played a smaller role in administration.
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
“BIOPOLIS”: Biopolicy for Greener and More Livable Cities
Cadmus, 2013 Urban centers are the engines which must bear the brunt of required changes to meet climate change mitigation goals, whilst continuing to provide social and economic opportunities.
“BIOPOLIS”: Biopolicy for Greener and More Livable Cities
doaj
, 2017 This study takes one of the most commonplace and everyday experiences of the city – the high street – and explores its social value from the perspective of Londoners.
LSE Cities, Suzanne Mary, We Made That,
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Universities Scale Like Cities [PDF]
, 2012 Recent studies of urban scaling show that important socioeconomic city characteristics such as wealth and innovation capacity exhibit a nonlinear, particularly a power law scaling with population size.
van Raan, Anthony F. J.
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SSRN Electronic Journal, 2012 Many developing countries display remarkably high degrees of urban concentration that are incommensurate with their levels of urbanization. The cost of excessively high levels of urban concentration can be very high in terms of overpopulation, congestion, and productivity growth.
Karayalcin, Cem, Yilmazkuday, Hakan
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Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
The real city - the mental city
Back to the Sense of the City: International Monograph Book, 2016 The search for relationships and dependencies between the real city and its mental image, may prove to be a key to understanding and reading the needs of the residents, primarily related to safety and comfort of living, as well as the location of places conducive to the development of social bonds.
Gibała-Kapecka, Beata, Kapecki, Tomasz
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