Results 161 to 170 of about 512,389 (298)

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Single Center, Open-Label, Randomized Crossover Trial on Drug-Drug Interactions of Levothyroxine/Magnesium-Citrate and Levothyroxine/Magnesium-Aspartate in Healthy Subjects-The ThyroMag Trial

M. Attinger, Stefanie von Felten, Claudia Lourenço Rodrigues, Jan Krützfeldt, Lorenz Risch, Jérôme Bonzon   +5 more
openalex   +1 more source

Acute versus chronic supplementation of sodium citrate on 200 m performance in adolescent swimmers [PDF]

, 2014
C F J Russell, Efthymios Papadopoulos, Yasmeen Mezil, Greg D. Wells, Michael J. Plyley, M. J. Greenway, Panagiota Klentrou   +6 more
openalex   +1 more source

Bivalirudin Stability in Citrated Plasma and Citrated Whole Blood

Archives of Pathology & Laboratory Medicine, 2023
Karen, Bruzdoski, Vadim, Kostousov, Jun, Teruya   +2 more
openaire   +2 more sources

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Albumin-corrected calcium ratios for citrate accumulation increase detection and improve mortality prediction in continuous kidney replacement therapy. [PDF]

Crit Care
Khawaja I, Gopireddy NSR, Grover S, Radford G, Fraer M, Nizar JM, Griffin BR.   +6 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Silver citrate engineered NiCo₂S₄/MOF-derived oxide@carbon frameworks for high-energy hybrid supercapacitors. [PDF]

RSC Adv
Sajid A, Marwat MA, Mohsin H, Shah SS, Karim MA, Abdul Karim MR, Tariq M, Ehsan Z, Arif A, Ghazanfar E.   +9 more
europepmc   +1 more source

Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment

, 2020
Zachary D. Blount, Rohan Maddamsetti, Nkrumah A. Grant, Sumaya T Ahmed, Tanush Jagdish, Jessica Baxter, Brooke A. Sommerfeld, Alice Tillman, Jeremy P. Moore, Joan L. Slonczewski, Jeffrey E. Barrick, Richard E. Lenski   +11 more
openalex   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source