Results 61 to 70 of about 346,140 (362)

Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]

, 2020
Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo, Freeman, Scott, Graham, Brian B, Gu, Sue, Hernandez-Saavedra, Daniel, Kassa, Biruk, Kumar, Rahul, Lee, Michael H, Mickael, Claudia, Reisz, Julie A, Sanders, Linda, Stenmark, Kurt R, Tuder, Rubin M   +12 more
core   +1 more source

Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction

Molecular Metabolism, 2022
Objective: One-carbon metabolism is routinely dysregulated in nonalcoholic fatty liver disease. This includes decreased glycine N-methyltransferase (GNMT), a critical regulator of s-adenosylmethionine (SAM).
Ferrol I. Rome, Curtis C. Hughey
doaj   +1 more source

c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction. [PDF]

PLoS ONE, 2015
Hypertrophic stimuli cause transcription of the proto-oncogene c-Myc (Myc). Prior work showed that myocardial knockout of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction.
Dolena Ledee, Lincoln Smith, Margaret Bruce, Masaki Kajimoto, Nancy Isern, Michael A Portman, Aaron K Olson   +6 more
doaj   +1 more source

Mass Production of LiFePO4/C Powders by Large Type Spray Pyrolysis Apparatus and Its Application to Cathode for Lithium Ion Battery

International Journal of Chemical Engineering, 2010
Spherical LiFePO4/C powders were successfully produced at a rate of 100 g/h using a large type spray pyrolysis apparatus. Organic compounds such as citric acid and sucrose were used as carbon sources.
Shinsuke Akao, Motofumi Yamada, Takayuki Kodera, Takashi Ogihara   +3 more
doaj   +1 more source

Shape memory epoxy vitrimers based on DGEBA crosslinked with dicarboxylic acids and their blends with citric acid [PDF]

, 2016
Thermosetting polymers were synthesized from a commercial epoxy resin (diglycidyl ether of bisphenol A, DGEBA) and tricarboxylic (citric, CA) and different dicarboxylic (sebacic, SA and glutaric, GA) acids.
Altuna, Facundo Ignacio, Hoppe, Cristina Elena, Williams, Roberto Juan Jose   +2 more
core   +1 more source

Development and application of an assay for uranyl complexation by fungal metabolites, including siderophores [PDF]

, 2003
An assay to detect UO2 2+ complexation was developed based on the chrome azurol S (CAS) assay for siderophores (B. Schwyn and J. B. Neilands, Anal. Biochem.
Collison, David, Halliday, Verity, Livens, Francis R., Renshaw, Joanna C., Robson, Geoffrey D., Taylor, Robin J., Trinci, Anthony P J, Wiebe, Marilyn G.   +7 more
core   +2 more sources

Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo

BMC Cancer, 2019
Background While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years.
Kensaku Abe, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroyuki Tsuchiya   +4 more
doaj   +1 more source

Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]

, 2013
Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core   +1 more source

Sensitive and Reproducible Mass Spectrometry-Compatible RP-UHPLC Analysis of Tricarboxylic Acid Cycle and Related Metabolites in Biological Fluids: Application to Human Urine.

Analytical Chemistry, 2020
We describe a method for the analysis of organic acids, including those of the tricarboxylic acid cycle (TCA cycle), by mixed-mode reversed-phase chromatography, on a CSH Phenyl-Hexyl column, to accomplish mixed-mode anion-exchange separations, which ...
Kerri M. Smith, I. Wilson, P. Rainville
semanticscholar   +1 more source

Anaplerotic Therapy Using Triheptanoin in Two Brothers Suffering from Aconitase 2 Deficiency

Metabolites
Citric acid cycle deficiencies are extremely rare due to their central role in energy metabolism. The ACO2 gene encodes the mitochondrial isoform of aconitase (aconitase 2), the second enzyme of the citric acid cycle.
Maximilian Penkl, Johannes A. Mayr, René G. Feichtinger, Ralf Reilmann, Otfried Debus, Manfred Fobker, Anja Penkl, Janine Reunert, Stephan Rust, Thorsten Marquardt   +9 more
doaj   +1 more source