Results 41 to 50 of about 124,230 (290)

Mass Production of LiFePO4/C Powders by Large Type Spray Pyrolysis Apparatus and Its Application to Cathode for Lithium Ion Battery

International Journal of Chemical Engineering, 2010
Spherical LiFePO4/C powders were successfully produced at a rate of 100 g/h using a large type spray pyrolysis apparatus. Organic compounds such as citric acid and sucrose were used as carbon sources.
Shinsuke Akao, Motofumi Yamada, Takayuki Kodera, Takashi Ogihara   +3 more
doaj   +1 more source

Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction

Molecular Metabolism, 2022
Objective: One-carbon metabolism is routinely dysregulated in nonalcoholic fatty liver disease. This includes decreased glycine N-methyltransferase (GNMT), a critical regulator of s-adenosylmethionine (SAM).
Ferrol I. Rome, Curtis C. Hughey
doaj   +1 more source

Regulation of Citric Acid Cycle by Calcium

Journal of Biological Chemistry, 1989
The relationship of extramitochondrial Ca2+ to intramitochondrial Ca2+ and the influence of intramitochondrial free Ca2+ concentrations on various steps of the citric acid cycle were evaluated. Ca2+ was measured using the Ca2+ sensitive fluorescent dye fura-2 trapped inside the rat heart mitochondria.
B, Wan, K F, LaNoue, J Y, Cheung, R C, Scaduto   +3 more
openaire   +2 more sources

Applications of Graphene Quantum Dots in Biomedical Sensors [PDF]

, 2020
Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow ...
Altintas, Zeynep, Mansuriya, Bhargav D.
core   +1 more source

Citric acid production by Yarrowia lipolytica from crude glycerol: Influence of oxygen mass transfer rate (OTR) [PDF]

, 2015
Glycerol from biodiesel industry, which is available in high amounts nowadays, is a renewable low-cost substrate that can be used for many biotechnological applications.
Belo, Isabel, Ferreira, Patrícia, Mota, M.   +2 more
core   +1 more source

Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo

BMC Cancer, 2019
Background While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years.
Kensaku Abe, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroyuki Tsuchiya   +4 more
doaj   +1 more source

Anaplerotic Therapy Using Triheptanoin in Two Brothers Suffering from Aconitase 2 Deficiency

Metabolites
Citric acid cycle deficiencies are extremely rare due to their central role in energy metabolism. The ACO2 gene encodes the mitochondrial isoform of aconitase (aconitase 2), the second enzyme of the citric acid cycle.
Maximilian Penkl, Johannes A. Mayr, René G. Feichtinger, Ralf Reilmann, Otfried Debus, Manfred Fobker, Anja Penkl, Janine Reunert, Stephan Rust, Thorsten Marquardt   +9 more
doaj   +1 more source

A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β-Lactam Stress

mBio, 2013
A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle).
Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, Paul D. Fey   +14 more
doaj   +1 more source

c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction. [PDF]

PLoS ONE, 2015
Hypertrophic stimuli cause transcription of the proto-oncogene c-Myc (Myc). Prior work showed that myocardial knockout of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction.
Dolena Ledee, Lincoln Smith, Margaret Bruce, Masaki Kajimoto, Nancy Isern, Michael A Portman, Aaron K Olson   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source