Results 31 to 40 of about 4,366,662 (271)

Innovation in the citric acid fermentation

, 2023
Citric acid, also known as 2-hydroxypropane-1,2,3-tricarboxylic acid, is a crucial metabolic intermediate that serves as the starting point for the tricarboxylic acid (TCA) cycle, a major energy-yielding metabolic pathway in cells.
Hernández Neira, Natalia Alejandra
core  

The Citric Acid Cycle

, 2012
Educação Superior::Ciências Biológicas::BioquímicaPresents the cycle of the citric acid, also known as tricarboxylic acid (TCA) cycleGeneral ...
LearnersTV
core   +3 more sources

Mass Production of LiFePO4/C Powders by Large Type Spray Pyrolysis Apparatus and Its Application to Cathode for Lithium Ion Battery

International Journal of Chemical Engineering, 2010
Spherical LiFePO4/C powders were successfully produced at a rate of 100 g/h using a large type spray pyrolysis apparatus. Organic compounds such as citric acid and sucrose were used as carbon sources.
Shinsuke Akao, Motofumi Yamada, Takayuki Kodera, Takashi Ogihara   +3 more
doaj   +1 more source

Identification of CmACL genes in melon and analysis of their potential functions in fruit sugar and acid accumulation

Frontiers in Plant Science, 2023
Citric acid is the most important organic acid in melon and has a great influence on fruit flavor quality. ATP-citrate (pro-S) lyase (ACL) is a key regulator in the acetyl-CoA pathway and plays an important role in citric acid metabolism.
Kaili Ren, Weiping Kong, Taoxia Tang, Hong Cheng   +3 more
doaj   +1 more source

Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo

BMC Cancer, 2019
Background While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years.
Kensaku Abe, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroyuki Tsuchiya   +4 more
doaj   +1 more source

Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction

Molecular Metabolism, 2022
Objective: One-carbon metabolism is routinely dysregulated in nonalcoholic fatty liver disease. This includes decreased glycine N-methyltransferase (GNMT), a critical regulator of s-adenosylmethionine (SAM).
Ferrol I. Rome, Curtis C. Hughey
doaj   +1 more source

Anaplerotic Therapy Using Triheptanoin in Two Brothers Suffering from Aconitase 2 Deficiency

Metabolites
Citric acid cycle deficiencies are extremely rare due to their central role in energy metabolism. The ACO2 gene encodes the mitochondrial isoform of aconitase (aconitase 2), the second enzyme of the citric acid cycle.
Maximilian Penkl, Johannes A. Mayr, René G. Feichtinger, Ralf Reilmann, Otfried Debus, Manfred Fobker, Anja Penkl, Janine Reunert, Stephan Rust, Thorsten Marquardt   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β-Lactam Stress

mBio, 2013
A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle).
Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, Paul D. Fey   +14 more
doaj   +1 more source

Transcriptome analysis provides insights into the root response of Chinese fir to phosphorus deficiency

BMC Plant Biology, 2021
Background Phosphorus is one of the essential elements for plant growth and development, but available phosphorus (Pi) content in many soil types is low.
Wanting Chen, Mengyan Zhou, Mingzhen Zhao, Ranhong Chen, Mulualem Tigabu, Pengfei Wu, Ming Li, Xiangqing Ma   +7 more
doaj   +1 more source