Results 131 to 140 of about 2,684 (181)
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Antiprotozoal activity in citrinin
Bulletin of Environmental Contamination and Toxicology, 1976Citrinin has an inhibitory effect on growth of T. pyriformis. Citrinin also caused a shift to smaller cell size, particularly at the higher concentrations (25, 50 and 100 mug/ml). The mycotoxin exerted only a marginal effect on the respiration of T. pyriformis; but citrinin (25 mug/ml) induced an inhibitory effect on DNA, RNA and protein content.
A W, Hayes, H E, Birkhead, E A, Hall
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Interaction of citrinin and ochratoxin A
Natural Toxins, 1994AbstractThe mycotoxins citrinin and ochratoxin A are produced in common by some molds and have been found together in a number of foods and animal feeds. We used in vitro tests to determine if the Same effects are produced by these two mycotoxins when they act both independently and together.
R C, Braunberg +3 more
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Citrinin mycotoxicosis in the rabbit
Food and Chemical Toxicology, 1983In three trials, single or multiple doses of citrinin dissolved in 0.5 N-NaOH and adjusted to neutral pH with HCl were given to rabbits by either the oral or intraperitoneal route. The 72-hr LD50 was 50 mg/kg body weight by intraperitoneal administration and 134 mg/kg by the oral route.
C, Hanika, W W, Carlton, J, Tuite
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Citrinin mycotoxicosis in the mouse
Food and Cosmetics Toxicology, 1977Abstract Citrinin was mixed in a purified diet for feeding to mice or was dissolved in sodium hydroxide (NaOH) or in equal parts of dimethylsulphoxide (DMSO) and 50% ethanol (EtOH) for administration by the ip, sc and oral routes. The single-dose LD 50 values determined in male mice at 72 hr for citrinin dissolved in DMSO-50%EtOH were 58, 73 and 112
W H, Jordon, W W, Carlton, G A, Sansing
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Zeitschrift für Ernährungswissenschaft, 1992
Citrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy and Urinary Tract Tumours" held in Lyon in June 1991 (12).
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Citrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy and Urinary Tract Tumours" held in Lyon in June 1991 (12).
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Mycotoxin Research, 2001
Despite the wide distribution of citrinin-producingPenicillium spp. there are only rare reports about the occurence of this mycotoxin in foodstuffs. Particularly, the discrepancy between the common detection of the applerotting fungusP expansum and the complete lack of data about the occurrence of citrinin in apple-based foods is noteworthy.
R, Dietrich, A, Schmid, E, Märtlbauer
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Despite the wide distribution of citrinin-producingPenicillium spp. there are only rare reports about the occurence of this mycotoxin in foodstuffs. Particularly, the discrepancy between the common detection of the applerotting fungusP expansum and the complete lack of data about the occurrence of citrinin in apple-based foods is noteworthy.
R, Dietrich, A, Schmid, E, Märtlbauer
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Journal of the Chemical Society, Chemical Communications, 1980
The biosynthetic pathway to citrinin is elucidated by incorporation studies with advanced precursors; the first step of biosynthesis involves methylation of a pentaketide, followed by cyclization, reduction to the ketoaldehyde and then to the hydroxyaldehyde, dehydration, and finally oxidation of the methyl group at C(7) to a carboxy-group.
L. Colombo +4 more
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The biosynthetic pathway to citrinin is elucidated by incorporation studies with advanced precursors; the first step of biosynthesis involves methylation of a pentaketide, followed by cyclization, reduction to the ketoaldehyde and then to the hydroxyaldehyde, dehydration, and finally oxidation of the methyl group at C(7) to a carboxy-group.
L. Colombo +4 more
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Experientia, 1975
Observations from preliminary experiments to discover the phytotoxicity, if any, of the fungal metabolite, citrinin, are presented. There seems to be a positive indication, warranting further investigation.
C. Damodaran +5 more
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Observations from preliminary experiments to discover the phytotoxicity, if any, of the fungal metabolite, citrinin, are presented. There seems to be a positive indication, warranting further investigation.
C. Damodaran +5 more
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Citrinin mycotoxicosis in beagle dogs
Food and Cosmetics Toxicology, 1974Abstract Three trials were completed in which young beagle dogs were either fed a citrinin-containing culture of Penicillium citrinum (Trial I) or were administered pure citrinin either ip (Trial II) or orally (Trial III). Dogs fed the fungal culture and those given 20 or 40 mg pure citrinin/kg body weight developed renal disease.
W W, Carlton +3 more
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Citrinin mycotoxicosis in the guinea-pig
Food and Cosmetics Toxicology, 1977Abstract Citrinin was dissolved in dimethylsulphoxide-ethanol solution and administered daily for 14 days by gastric intubation to young male and female guinea-pigs. Under these conditions, the LD 50 of citrinin was 43 mg/kg/day for both sexes. Loss of body weight was the most consistent clinical feature of citrinin toxicity.
H.L. Thacker, W.W. Carlton, G.A. Sansing
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