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Citrinin mycotoxicosis in the syrian hamster
Food and Cosmetics Toxicology, 1978Abstract Citrinin, dissolved in either a solution of equal parts of dimethylsulphoxide (DMSO) and 50% ethanol (EtOH) or 0.5 N -sodium hydroxide (NaOH), was administered by the ip or oral route to weanling Syrian hamsters. The single-dose ip LD 50 for citrinin dissolved in DMSO-50% EtOH, determined 72 hr after injection, was 66 mg/kg: for citrinin ...
W.H. Jordan, W.W. Carlton, G.A. Sansing
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Citrinin mycotoxicosis in broiler chickens
Food and Cosmetics Toxicology, 1981Citrinin, a mycotoxin, was administered to chickens by crop gavage in dimethylsulphoxide-70% ethanol (3:1, v/v) or mixed with the diet (commercial starter mash) in four separate trials. The single-dose oral LD50 value in 7-day-old male broiler chicks was found to be 95 mg/kg. The administration of seven daily doses of citrinin equal to a half and three-
N A, Mehdi, W W, Carlton, J, Tuite
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Archives of Toxicology, 2014
Citrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by several species of the genera Aspergillus, Penicillium and Monascus. Both can be present as contaminants in various food commodities and in animal feed. The occurrence and toxicity of OTA and human exposure have been intensively studied, but for CIT such data are scarce by comparison ...
Wolfram, Föllmann +2 more
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Citrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by several species of the genera Aspergillus, Penicillium and Monascus. Both can be present as contaminants in various food commodities and in animal feed. The occurrence and toxicity of OTA and human exposure have been intensively studied, but for CIT such data are scarce by comparison ...
Wolfram, Föllmann +2 more
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The structure of citrinin in vivo
Journal of the Chemical Society, Perkin Transactions 1, 19871 H- and 13C-N.m.r. spectroscopy have been used to show that in aqueous solution at physiological pH the antibiotic citrinin exists not as the quinone methide (1) but as a diastereoisomeric mixture of hydrates. The equilibrium between the two diastereoisomers is slow, suggesting that citrinin, which is believed to interact with deoxyribonucleic acid
Jill Barber +3 more
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Chemical Structure of Citrinin
Nature, 1961IN our search for new antibiotics from fungi we have isolated a substance, S-52, a metabolic product of an unidentified Penicillium. From the results of paper-chromatographic investigations and from its other properties we believed the substance to be identical with citrinin.
ŠTEFAN KOVÁČ +3 more
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Journal of the American Chemical Society, 1948
T S, GORE, T B, PANSE, K, VENKATARAMAN
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T S, GORE, T B, PANSE, K, VENKATARAMAN
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