Results 91 to 100 of about 258,864 (309)

POS-469 ENHANCING PATIENT CARE BY PARTNERING WITH PATIENTS IN KIDNEY HEALTH RESEARCH

Kidney International Reports, 2021
L. Getchell, M. Beaucage, D. Hillier, A. MacPhee, H. Vorster, G. Pollock   +5 more
doaj   +1 more source

Frailty and CKD [PDF]

Clinical Journal of the American Society of Nephrology, 2019
Frailty is a process theorized to be, at least in part, attributable to chronic inflammation marked by hormonal changes, anorexia, decreased muscle strength, and depression. The phenotypic definition operationalized by Fried et al. ([1][1]) includes any three or more of the following: weight loss,
openaire   +2 more sources

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

A coaching program to improve dietary intake of patients with CKD : ENTICE-CKD [PDF]

, 2020
The dietary self-management of CKD is challenging. Telehealth interventions may provide an effective delivery method to facilitate sustained dietary change.This pilot, randomized, controlled trial evaluated secondary and exploratory outcomes after a ...
Craig, Jonathan C., Marina M. Reeves, Jonathan C. Craig, Johnson, David W., Katrina L. Campbell, Jagadeesh Kurtkoti, Reidlinger, Dianne P., David W. Johnson, Reeves, Marina M., Johnson, David W, Kurtkoti, Jagadeesh, Campbell, Katrina L, Reidlinger, Dianne P, Allison Tong, Tammy Hoffmann, Kirsten Howard, Rathika Krishnasamy, Reeves, Marina M, Dianne P. Reidlinger, Marguerite Conley, Tong, Allison, Krishnasamy, Rathika, Howard, Kirsten, Palmer, Suetonia C., Hoffmann, Tammy, Conley, Marguerite, Campbell, Katrina L., Palmer, Suetonia C, Jaimon T. Kelly, Suetonia C. Palmer, Craig, Jonathan C, Kelly, Jaimon T, Kelly, Jaimon T.   +32 more
core   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

An optimized 5/6 nephrectomy mouse model based on unilateral kidney ligation and its application in renal fibrosis research

Renal Failure, 2019
5/6 Nephrectomy (PNx) on rat and mouse mimics renal failure after loss of kidney function in human, and it has been widely used in CKD researches. However, existing methods for PNx model construction present high mortality of animals after modeling due ...
Rui-Zhi Tan, Xia Zhong, Jian-Chun Li, Yu-Wei Zhang, Ying Yan, Yuan Liao, Dan Wen, Hui Diao, Li Wang, Hong-Chun Shen   +9 more
doaj   +1 more source

CKD-Associated Pruritus and Clinical Outcomes in Nondialysis CKD

Kidney Medicine
Itching is a frequent symptom experienced by people with chronic kidney disease (CKD). We investigated the associations of CKD-associated pruritus (CKD-aP) with clinical outcomes.This was a longitudinal cohort study.Patients from Brazil, France, and the United States enrolled in the Chronic Kidney Disease Outcomes and Practice Patterns Study (CKDopps ...
Jennifer S. Scherer, Charlotte Tu, Ronald L. Pisoni, Elodie Speyer, Antonio A. Lopes, Warren Wen, Frederique Menzaghi, Joshua Cirulli, Natalia Alencar de Pinho, Roberto Pecoits-Filho, Angelo Karaboyas, Antonio Lopes, Roberto Pecoits-Filho, Christian Combe, Christian Jacquelinet, Ziad Massy, Benedicte Stengel, Johannes Duttlinger, Danilo Fliser, Gerhard Lonnemann, Helmut Reichel, Takashi Wada, Kunihiro Yamagata, Ron Pisoni, Bruce Robinson, Viviane Calice da Silva, Ricardo Sesso, Elodie Speyer, Koichi Asahi, Junichi Hoshino, Ichiei Narita, Rachel Perlman, Friedrich Port, Nidhi Sukul, Michelle Wong, Eric Young, Jarcy Zee   +36 more
openaire   +5 more sources

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

Advanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang, Yan Zhang, Fang Bai, Shankui Qian, Feng Feng, Fangyi Lu, Jiahui Fan, Kuipeng Yu, Xiangdong Yang   +8 more
wiley   +1 more source

Intervention to diminish dehydration and kidney damage among sugarcane workers

Scandinavian Journal of Work, Environment & Health, 2018
OBJECTIVE: The aim of this study was to assess the potential to reduce kidney function damage during the implementation of a water, rest, shade (WRS) and efficiency intervention program among sugarcane workers. METHODS: A WRS intervention program adapted
David H Wegman, Jenny Apelqvist, Matteo Bottai, Ulf Ekström, Ramón García-Trabanino, Jason Glaser, Christer Hogstedt, Kristina Jakobsson, Emmanuel Jarquín, Rebekah A I Lucas, Ilana Weiss, Catharina Wesseling, Theo Bodin, The Work Health and Efficiency (WE) Program Working Group   +13 more
doaj   +1 more source

PULSED-WAVE DOPPLER DERIVED INDICES IN CHRONIC KIDNEY DISEASE (CKD) IN DOGS

, 2023
PULSED-WAVE DOPPLER DERIVED INDICES IN CHRONIC KIDNEY DISEASE (CKD) IN ...
PULSED-WAVE DOPPLER DERIVED INDICES IN CHRONIC KIDNEY DISEASE (CKD) IN DOGS
core   +1 more source