Results 121 to 130 of about 343,907 (366)

Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial.

American Journal of Kidney Diseases, 2018
RATIONALE & OBJECTIVE Epidemiologic and clinical studies have suggested that urate-lowering therapy may slow the progression of chronic kidney disease (CKD). However, definitive evidence is lacking.
K. Kimura, T. Hosoya, S. Uchida, M. Inaba, H. Makino, S. Maruyama, S. Ito, Tetsuya Yamamoto, Y. Tomino, I. Ohno, Y. Shibagaki, S. Iimuro, N. Imai, M. Kuwabara, H. Hayakawa, H. Ohtsu, Y. Ohashi   +16 more
semanticscholar   +1 more source

The spatial analysis of diagnosed Chronic Kidney Disease in Nigeria: A case study of Edo State [PDF]

, 2012
The thesis explores the severity of diagnosed chronic kidney disease (CKD) with particular reference to its impact in Edo state, Nigeria. There has been a scarcity of studies on the prevalence and spatial patterns of CKD in developing countries even ...
Oviasu, Osaretin
core  

Americans' Use of Dietary Supplements That Are Potentially Harmful in CKD [PDF]

, 2013
BACKGROUND: The prevalence in the United States of dietary supplement use that may be harmful to those with chronic kidney disease (CKD) is unknown. We sought to characterize potentially harmful supplement use by individual CKD status.
Tuot, Delphine S, Plantinga, Laura C, Saran, Rajiv, Grubbs, Vanessa, Hedgeman, Elizabeth, Saydah, Sharon, Team, Centers for Disease Control and Prevention CKD Surveillance, Rolka, Deborah, Powe, Neil R   +8 more
core   +1 more source

Kidney failure, CKD progression and mortality after nephrectomy

, 2022
PURPOSE: This study tested the hypothesis that progression of chronic kidney disease (CKD) is less aggressive in patients whose primary cause of CKD was nephrectomy, compared with non-surgical causes.
Cameron, A, Lee, J, Venuthurupalli, Sree, Cameron, Anne, Diwan, Vishal, Tan, KS, Tan, Ken-Soon, Venuthurupalli, S, Gobe, Glenda C., Hoy, Wendy E., Zhang, Jianzhen, Diwan, V, Ellis, RJ, Hoy, WE, Healy, Helen G., Lee, Jeremy, Gobe, GC, Ellis, Robert J., Healy, HG, Zhang, J   +19 more
core   +1 more source

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

An optimized 5/6 nephrectomy mouse model based on unilateral kidney ligation and its application in renal fibrosis research

Renal Failure, 2019
5/6 Nephrectomy (PNx) on rat and mouse mimics renal failure after loss of kidney function in human, and it has been widely used in CKD researches. However, existing methods for PNx model construction present high mortality of animals after modeling due ...
Rui-Zhi Tan, Xia Zhong, Jian-Chun Li, Yu-Wei Zhang, Ying Yan, Yuan Liao, Dan Wen, Hui Diao, Li Wang, Hong-Chun Shen   +9 more
doaj   +1 more source

Incidence of AKI and CKD in a large population of living kidney donors

, 2022
openIntroduzione: Il trapianto di rene è la migliore terapia per i pazienti con IRC e il trapianto da donatore vivente rappresenta una delle strategie più efficaci e sicure per soddisfare la crescente domanda di organi per il trapianto.
MACULAN, MARCO
core  

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Intervention to diminish dehydration and kidney damage among sugarcane workers

Scandinavian Journal of Work, Environment & Health, 2018
OBJECTIVE: The aim of this study was to assess the potential to reduce kidney function damage during the implementation of a water, rest, shade (WRS) and efficiency intervention program among sugarcane workers. METHODS: A WRS intervention program adapted
David H Wegman, Jenny Apelqvist, Matteo Bottai, Ulf Ekström, Ramón García-Trabanino, Jason Glaser, Christer Hogstedt, Kristina Jakobsson, Emmanuel Jarquín, Rebekah A I Lucas, Ilana Weiss, Catharina Wesseling, Theo Bodin, The Work Health and Efficiency (WE) Program Working Group   +13 more
doaj   +1 more source

Arterial Stiffness in the Heart Disease of CKD.

Journal of the American Society of Nephrology, 2019
CKD frequently leads to chronic cardiac dysfunction. This complex relationship has been termed as cardiorenal syndrome type 4 or cardio-renal link. Despite numerous studies and reviews focused on the pathophysiology and therapy of this syndrome, the role
L. Zanoli, P. Lentini, M. Briet, P. Castellino, A. House, G. London, L. Malatino, P. McCullough, D. Mikhailidis, P. Boutouyrie   +9 more
semanticscholar   +1 more source