Results 201 to 210 of about 40,355 (313)

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso   +3 more
wiley   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Accelerating Perovskite Solar Cell Development Through High‐Throughput Technologies: Computational Simulation, Automated Experimentation, and Intelligent Integration

open access: yesBattery Energy, Volume 5, Issue 4, July 2026.
Moving beyond traditional trial‐and‐error, this review explores how integrating high‐throughput computational simulations, automated experimentation, and machine learning significantly accelerates perovskite solar cell development. By establishing intelligent, closed‐loop workflows, these synergistic technologies pave the way for fully autonomous ...
Yiming Wang   +5 more
wiley   +1 more source

Updates on Minimally Invasive Treatment of Adrenal Tumors. [PDF]

open access: yesCancers (Basel)
Akkus D, Berber E, Pérez-Soto RH.
europepmc   +1 more source

Item Response Theory Analysis of the Classroom Level Adversity Scale

open access: yesPsychology in the Schools, Volume 63, Issue 7, Page 1105-1116, July 2026.
ABSTRACT The Classroom Level Adversity Scale (CLA) captures teachers' perceptions of the overall needs and challenges present in their classrooms. It reflects a collective classroom characteristic based on teacher report, providing insight into the degree of ecological risk teachers perceive when working with their students.
Allyson L. Hayward   +2 more
wiley   +1 more source

Red‐Pi: A Low‐Cost Red Teaming Platform for Water Infrastructure Security Assessment

open access: yesSECURITY AND PRIVACY, Volume 9, Issue 4, July/August 2026.
ABSTRACT The water and wastewater sector faces growing cyber threats due to rapid digitalization and the use of IoT‐based control systems. Many utilities manage essential services that affect public health and the environment but do not have enough cybersecurity staff and cannot afford regular security tests.
Agustin Di Bartolo   +5 more
wiley   +1 more source

Influência da suplementação de ácido linoleico conjugado (CLA) sobre a composição corporal de homens e mulheres

open access: yesRevista Brasileira de Nutrição Esportiva, 2012
Cristiane Spricigo de Lima   +1 more
doaj  

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