Results 101 to 110 of about 1,914 (161)

Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020

mBio
Since 2020, H5N1 highly pathogenic avian influenza (HPAI) viruses of clade 2.3.4.4b have been rapidly spreading in wild birds but have also caused a large number of mammalian infections and more than 70 known human cases. Importantly, this H5N1 clade has
Enikő Hermann, Florian Krammer
doaj   +1 more source

Dose-Dependent Effect of DNA Vaccine pVAX-H5 Encoding a Modified Hemagglutinin of Influenza A (H5N8) and Its Cross-Reactivity Against A (H5N1) Influenza Viruses of Clade 2.3.4.4b

Viruses
Highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b viruses are widespread in wild and domestic birds, causing severe economic damage to the global poultry industry.
Andrey P. Rudometov, Victoria R. Litvinova, Andrei S. Gudymo, Ksenia I. Ivanova, Nadezhda B. Rudometova, Denis N. Kisakov, Mariya B. Borgoyakova, Lyubov A. Kisakova, Vladimir A. Yakovlev, Elena V. Tigeeva, Danil I. Vahitov, Kristina P. Makarova, Natalia P. Kolosova, Tatiana N. Ilyicheva, Vasiliy Yu. Marchenko, Artemiy A. Sergeev, Larisa I. Karpenko, Alexander A. Ilyichev   +17 more
doaj   +1 more source

Incursion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Brazil, 2023

Emerging Infectious Diseases
We report 4 highly pathogenic avian influenza A(H5N1) clade 2.3.4.4.b viruses in samples collected during June 2023 from Royal terns and Cabot's terns in Brazil. Phylodynamic analysis revealed viral movement from Peru to Brazil, indicating a concerning spread of this clade along the Atlantic Americas migratory bird flyway.
Andreina Carvalho de Araújo, Laura Morais Nascimento Silva, Andrew Yong Cho, Márcio Repenning, Deyvid Amgarten, Ana Paula de Moraes, Fernanda Malta, Michael Miller, Erick G. Dorlass, Soledad Palameta, Daniele Bruna L. Oliveira, Jansen de Araújo, Clarice Weis Arns, Edison L. Durigon, João Renato R. Pinho, Dong-Hun Lee, Helena Lage Ferreira   +16 more
openaire   +3 more sources

Effect of Prior Influenza A(H1N1)pdm09 Virus Infection on Pathogenesis and Transmission of Human Influenza A(H5N1) Clade 2.3.4.4b Virus in Ferret Model

Emerging Infectious Diseases
Reports of human infections with influenza A(H5N1) clade 2.3.4.4b viruses associated with outbreaks in dairy cows in the United States underscore the need to assess the potential cross-protection conferred by existing influenza immunity.
Xiangjie Sun, Jessica A. Belser, Zhu-Nan Li, Nicole Brock, Joanna A. Pulit-Penaloza, Troy J. Kieran, Claudia Pappas, Hui Zeng, Jessie C. Chang, Paul J. Carney, Brandon L. Bradley-Ferrell, James Stevens, Terrence M. Tumpey, Min Z. Levine, Taronna R. Maines   +14 more
doaj   +1 more source

Highly Pathogenic Clade 2.3.4.4b H5N1 Influenza Virus in Seabirds in France, 2022–2023

Transboundary and Emerging Diseases
In 2022, a very high number of wild bird deaths associated with the detection of highly pathogenic (HP) H5 avian influenza virus (AIV) lineage Gs/GD/96, clade 2.3.4.4b viruses were unusually observed in Europe between May and September, whereas prior to 2022 most of these HP H5 AIVs detected in wild birds in Europe were almost all detected between ...
Francois-Xavier Briand, Loïc Palumbo, Claire Martenot, Pascale Massin, Martine Cherbonnel, Rachel Busson, Katell Louboutin, Angelina Orosco, Carole Guillemoto, Florent Souchaud, Isabelle Pierre, Edouard Hirchaud, Manon Tasset, Yannick Blanchard, Nolwenn Le Moal, Anne Van De Wiele, Audrey Schmitz, Eric Niqueux, Béatrice Grasland   +18 more
openaire   +2 more sources

The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution

Nature Communications
Avian influenza H5N1 clade 2.3.4.4b viruses caused a global panzootic and, unexpectedly, widespread outbreaks in dairy cattle, therefore representing a pandemic threat.
Matthew L. Turnbull, Mohammad Khalid Zakaria, Nicole S. Upfold, Siddharth Bakshi, Callum Magill, Udeet Ranjan Das, Andrew T. Clarke, Laura Mojsiejczuk, Vanessa Herder, Kieran Dee, Nancy Liu, Monika Folwarczna, Georgios Ilia, Wilhelm Furnon, Verena Schultz, Hanting Chen, Ryan Devlin, Jack McCowan, Alex L. Young, Wai-Wai Po, Katherine Smollett, Muhammad Ahsan Yaseen, Rebecca Ross, Avanti Bhide, Bianca van Kekem, Ron A. M. Fouchier, Ana da Silva Filipe, Munir Iqbal, Ed Roberts, Joseph Hughes, Dirk Werling, Pablo R. Murcia, Massimo Palmarini   +32 more
doaj   +1 more source

Genetic features of avian influenza (A/H5N8) clade 2.3.4.4b isolated from quail in Egypt

Virus Research
Several genotypes of the highly pathogenic avian influenza (HPAI) virus H5N8 subtype within clade 2.3.4.4b continue to circulate in different species of domestic birds across Egypt. It is believed that quail contribute to virus replication and adaptation to other gallinaceous poultry species and humans.
Elhusseiny, Mohamed H., Elsayed, Moataz M., Mady, Wesam H., Mahana, Osama, Bakry, Neveen R., Abdelaziz, Ola, Arafa, Abdel-Sattar, Shahein, Momtaz A., Eid, Samah, Naguib, Mahmoud M.   +9 more
openaire   +4 more sources

Multiple introductions of highly pathogenic avian influenza H5N1 clade 2.3.4.4b into South America

Travel Medicine and Infectious Disease, 2023
Julian Ruiz-Saenz, Marlen Martinez-Gutierrez, Flor H. Pujol   +2 more
openaire   +2 more sources

Receptor basis of unusual tissue tropism of avian influenza H5N1 clade 2.3.4.4b virus in cattle. [PDF]

Sci Adv
Srinivas S, Chothe SK, Ramasamy S, Misra S, Nallipogu NC, LaBella L, Yeh YT, Wang M, Pepi LE, Pecoraro HL, Webb BT, Kuchipudi SV.   +11 more
europepmc   +1 more source

Mammary and respiratory infection of sheep with H5Nx clade 2.3.4.4b viruses with milk-mediated transmission to lambs. [PDF]

Sci Adv
Alkie TN, Embury-Hyatt C, Signore AV, Moffat E, Ramos D, Raj S, Hisanaga T, Ayilara I, Sullivan DS, Lloyd P, Pama L, Erdelyan CNG, Lang AS, Kobasa D, Ojkic D, Matheson L, Lung O, Poljak Z, Berhane Y.   +18 more
europepmc   +1 more source