Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Muscle Sparing Open Descending Thoracic Aortic Aneurysm Repair. [PDF]
Ribé L, Tanaka A, Afifi RO, Estrera AL.
europepmc +1 more source
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Inference of the 3D pressure field exerted by a single cell from a thin membrane transverse deformation. [PDF]
Bédel Q, Dupré L, Destainville N.
europepmc +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Stress and stiffness analysis of the multiple corrugated diaphragm under angular load based on plate and shell theory. [PDF]
Cao A, Jin H, Li W, Jiang S.
europepmc +1 more source
Optimizing noise control in flexible shells with bridging membrane discs variations. [PDF]
Alahmadi H, Afzal M, Alkuhayli N.
europepmc +1 more source
Computational modeling of surface energy effects on linear and nonlinear frequencies in different crystalline orientations of anodic aluminum micro-beams. [PDF]
Hajlaoui K +3 more
europepmc +1 more source
Investigating various nonlinear vibration problems using VIBRANT: A tool based on Abaqus and Python. [PDF]
Tüfekci M, Sevencan F, Yurdakul O.
europepmc +1 more source
Complex case of congenital pulmonary sequestration with successful "EXIT" procedure. [PDF]
Bernatavičienė R +3 more
europepmc +1 more source

