Results 71 to 80 of about 194,312 (252)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Clarification [PDF]

The American Naturalist, 2017
Daniela, Vergara, Jukka, Jokela, Curtis M, Lively   +2 more
openaire   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Zâhirî Usulcü İbn Hazm’ın Beyân’ın Tehiri Meselesine Yaklaşımı

Umde Dini Tetkikler Dergisi
Kelâm ve fıkıh usulü, İslam ilim geleneğinde erken dönemlerden itibaren Müslümanların gündemindeki temel meseleleri sistematik biçimde ele alan iki kritik disiplindir.
Yasin Akan
doaj   +1 more source

Folhas verdes, folhas secas, fibra do colmo e a clarificação do caldo de cana-de-açúcar Green leaves, dry leaves, stalk fiber and the clarification of sugarcane juice

Scientia Agricola, 2001
A presença de impurezas vegetais, como folhas verdes e secas, nos carregamentos de cana-de-açúcar entregues nas usinas de açúcar, tem preocupado os técnicos não somente por se tratar de um material sem qualquer valor tecnológico para processamento, como ...
Roberto Bovi, Gil Eduardo Serra
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

CLARIFICATION TO "COMPARATIVE ANALYSIS OF INDICATORS OF ECONOMIC EFFICIENCY OF CULTIVATION OF CHERRY SEEDLINGS WITH DRIP IRRIGATION" DOI: 10.12731/2658-6649-2024-16-1-722

Siberian Journal of Life Sciences and Agriculture
Nikolskaya O.A., Semenchenko E.V., Solonkin A.V. Comparative Analysis of Indicators of Economic Efficiency of Cultivation of Cherry Seedlings with Drip Irrigation. Siberian Journal of Life Sciences and Agriculture, 2024, vol. 16, no. 1, pp. 102-118. DOI:
Olga A. Nikolskaya, Elena V. Seminchenko, Andrey V. Solonkin   +2 more
doaj   +1 more source