Results 121 to 130 of about 55,171 (227)

Exploring the Molecular Mechanisms of Macrolide Resistance in Laboratory Mutant Helicobacter pylori

Antibiotics
Resistance to clarithromycin, a macrolide antibiotic used in the first-line treatment of Helicobacter pylori infection, is the most important cause of treatment failure. Although most cases of clarithromycin resistance in H.
Meltem Ayaş, Sinem Oktem-Okullu, Orhan Özcan, Tanıl Kocagöz, Yeşim Gürol   +4 more
doaj   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

The Association of a Positive Fecal Immunochemical Test With the Risk of Gastroesophageal Cancer: An Age‐Sex‐H. Pylori Exposure Matched Cohort Study and Cost‐Effectiveness Analysis

Helicobacter, Volume 31, Issue 2, March/April 2026.
ABSTRACT Background and Aims We evaluated the association between Fecal Immunochemical Test (FIT) results and the risk of gastroesophageal cancer (GEC) in a matched cohort, as well as the cost‐effectiveness of a one‐time esophagogastroduodenoscopy (EGD) for individuals who tested FIT‐positive.
Zohar Levi, Naim Abu‐Freha, Doron Boltin, Maya Aharoni Golan, Tom Konikoff, Orly Sneh Arbib, Rachel Gingold Belfer, Sapir Eizenstein, Alex Vilkin, Shiri Kusnir, Adi Turgeman, Tanya Babich, Moshe Leshno, Anath A. Flugelman, Hadar Edelman‐Klapper, Elizabeth Half‐Onn   +15 more
wiley   +1 more source

Detection of Helicobacter pylori and the Genotypes of Resistance to Clarithromycin, Fluoroquinolones, and Metronidazole in Gastric Biopsies: An In Silico Analysis to Help Understand Antibiotic Resistance

Current Issues in Molecular Biology
Antibiotic resistance in Helicobacter pylori is increasing rapidly and emerging as a major factor in treatment failure. We aimed to identify genetic mutations associated with resistance to clarithromycin (23S rRNA peptidyl transferase), fluoroquinolones (
Pedro Valada, Ana Mata, Rui M. M. Brito, Teresa Gonçalves, José A. Medeiros, Célia Nogueira   +5 more
doaj   +1 more source

Oral JAK Inhibitors as a Promising Therapeutic Strategy for Refractory Rosacea: A Systematic Review and Meta‐Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Rosacea is a chronic inflammatory dermatosis. While standard therapies exist, managing refractory subtypes remains a therapeutic challenge. Oral Janus kinase (JAK) inhibitors have emerged as potential alternatives, but systematic evidence is lacking. Aims To evaluate the efficacy and safety of oral JAK inhibitors for rosacea through
Yu Peng, Mingzi Sun, Jiayu Chen, Xubo Huang, Fengchuan Zhang   +4 more
wiley   +1 more source

Clinical Efficacy of Tofacitinib in Treating Granulomatous Reaction After Mesotherapy: A Case Series Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Mesotherapy, a widely utilized minimally invasive cosmetic procedure, carries potential risks of adverse reactions due to non‐standardized protocols and overuse. Delayed granulomatous reactions represent a chronic complication, imposing significant physical and psychological burdens on patients.
Chang Shu, Tao Zhang, Jia‐Wei Liu, Chen‐yu Zhu, Rou‐yu Fang, Qiu‐ning Sun, Nian Li, Feng Li   +7 more
wiley   +1 more source

Direct single dose mass delabelling of antibiotic allergy in pediatrics

Pediatric Allergy and Immunology, Volume 37, Issue 3, March 2026.
Abstract Background Unsubstantiated antibiotic allergy labels affect between 8% and 25% of the population worldwide. Current risk stratification tools, derived from adult data, are not validated for children. A simplified, multi‐patient protocol with minimal exclusion criteria is required to tackle the scale of this public health issue.
Sheena Coyne, Aideen Byrne, Amber Gill, Davina Henderson, Kara Tedford, Victoria Mc Donald, Helen O'Connor, Catherine Breen, Aisling Stafford, Maeve Kelleher, David Coghlan, Jonathan Hourihane   +11 more
wiley   +1 more source

Mycobacterium avium Infection in a Domestic Shorthair Cat Following Subdermal Hyaluronic Acid Filler Injection

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To describe the diagnosis and treatment of a Mycobacterium avium (M. avium) infection in a cat following subdermal hyaluronic acid (HA) filler injection. Animal Studied A five‐year‐old spayed female domestic shorthair cat with chronic inferior lateral entropion and chronic feline atopic skin syndrome (FASS).
Alexandra E. Bergen, Callie Miller, J. Seth Eaton, Lara M. Tomich, Jennifer L. Heyward, Taylor A. Opgenorth   +5 more
wiley   +1 more source

Cultural Recovery and Determination of Antimicrobial Susceptibility in Helicobacter pylori by Using Commercial Transport and Isolation Media [PDF]

, 2018
: Background: : Antimicrobial resistance of Helicobacter pylori is the main reason for eradication failure. We have studied the feasibility of a commercial transport medium for cultural recovery and subsequent drug susceptibility testing.
Bauerfeind, P., Bernardi, M., Fried, M., Yuen, B., Zbinden, R.   +4 more
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Evaluation eines Enzymimmunoassays und einer Real-Time PCR für den Nachweis von Helicobacter pylori in Stuhlmaterial von Kindern [PDF]

, 2011
Helicobacter pylori, ein gramnegatives Stäbchenbakterium, kann durch eine Invasion der Magenschleimhaut Erkrankungen wie die Typ B-Gastritis, die gastroduodenale Ulkuserkrankung, das Magenkarzinom sowie das MALT-Lymphom hervorrufen.
Lottspeich, Christian
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