Results 121 to 130 of about 62,320 (268)

The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Ecopipam is a first‐in‐class dopamine D1 receptor antagonist under investigation for the treatment of Tourette syndrome. This open‐label, fixed‐sequence, three‐cohort study evaluated whether ecopipam induces or inhibits cytochrome P450 (CYP) 1A2, CYP2B6, CYP2C19, CYP2D6, CYP3A4, organic anion‐transporting polypeptide (OATP) 1B1, and p ...
Virginia D. Schmith   +4 more
wiley   +1 more source

Acute hepatitis and haemolysis associated with doxycycline and rifampin administration in two weanling foals

open access: yesEquine Veterinary Education, Volume 38, Issue 2, Page e70-e77, February 2026.
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock   +7 more
wiley   +1 more source

Detection of Helicobacter pylori and the Genotypes of Resistance to Clarithromycin, Fluoroquinolones, and Metronidazole in Gastric Biopsies: An In Silico Analysis to Help Understand Antibiotic Resistance

open access: yesCurrent Issues in Molecular Biology
Antibiotic resistance in Helicobacter pylori is increasing rapidly and emerging as a major factor in treatment failure. We aimed to identify genetic mutations associated with resistance to clarithromycin (23S rRNA peptidyl transferase), fluoroquinolones (
Pedro Valada   +5 more
doaj   +1 more source

Best of United European Gastroenterology Week 2025

open access: yes
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
Iuliana Nenu   +3 more
wiley   +1 more source

Cultural Recovery and Determination of Antimicrobial Susceptibility in Helicobacter pylori by Using Commercial Transport and Isolation Media [PDF]

open access: yes, 2018
: Background: : Antimicrobial resistance of Helicobacter pylori is the main reason for eradication failure. We have studied the feasibility of a commercial transport medium for cultural recovery and subsequent drug susceptibility testing.
Bauerfeind, P.   +4 more
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