Results 101 to 110 of about 2,107,159 (261)

An Experience of Secular Metaphysic - Part I: Descartes [PDF]

open access: yesВестник Свято-Филаретовского института, 2014
The phenomenon of “secular metaphysics” is considered as special entertainment of reason seeking perfect clarity. It is demonstrated, that an attempt to reach the clarity by means of ideal constructing results in the creation of total systems.
Grigory Goutner
doaj  

Grammar Jam: Adding a Creative Editing Tactic

open access: yesPrompt, 2018
The author argues reading, hearing, and then composing musical lyrics involving grammatical concerns can help college writing students to edit more effectively for a song's grammar topic.
David Gillespie
doaj   +1 more source

Valuing a Spatially Variable Environmental Resource: Reducing Non-point Source Pollution in Green Bay, WI [PDF]

open access: yes
This article investigates the value of reducing non-point source pollution in Green Bay, WI. Using stated preference methods, we find the lower bound on the benefits of reducing runoff enough to universally increase water clarity by four feet is greater ...
Bishop, Richard C.   +2 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

O "TRACTATUS" DE WITTGENSTEIN COMO UM EDIFÍCIO COM TRAÇOS LOOSIANOS

open access: yesPrincípios, 2014
This article show the Adolf Loos’ ethical crusade against the ornament in architecture, and its influence in the thought of Wittgenstein. First, it shows his attack against the absurdity architectural of Ringstrasse.
José Fernando da Silva
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

LEX.CH.IT: A CORPUS FOR MICRO-DIACHRONIC LINGUISTIC INVESTIGATIONS OF SWISS NORMATIVE ACTS IN ITALIAN

open access: yesComparative Legilinguistics, 2019
The aim of this paper is to present LEX.CH.IT, a corpus for micro-diachronic linguistic investigations of Swiss normative acts in Italian. Italian has a peculiar position as an official minority translation language within the Swiss institutional system.
Paolo CANAVESE
doaj   +2 more sources

Radio Spectrum and the Disruptive Clarity OF Ronald Coase. [PDF]

open access: yes
In the Federal Communications Commission, Ronald Coase (1959) exposed deep foundations via normative argument buttressed by astute historical observation. The government controlled scarce frequencies, issuing sharply limited use rights.
David Porter   +2 more
core  

The Common Core Debate [PDF]

open access: yes, 2014
The Common Core State Standards (CCSS) have ignited a passionate national debate about the standards that guide the education of our nation’s and state’s students.
Ash, Jennifer W.   +2 more
core   +2 more sources

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