Results 101 to 110 of about 768,011 (297)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The aim of this paper is to present LEX.CH.IT, a corpus for micro-diachronic linguistic investigations of Swiss normative acts in Italian. Italian has a peculiar position as an official minority translation language within the Swiss institutional system.
Paolo CANAVESE
doaj +2 more sources
The famous pensée on examples (Sellier 454) usually puzzles the reader with the false symmetry of these propositions: “When one wishes to demonstrate a general principle, one must provide the specific rule for a particular case.
Éric Méchoulan
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
clarity-h2020/csis-helpers-js: v0.6.4
JavaScript Helper Library for communicating with Drupal 8 JSON ...
Pascal Dihé, DanielRodera
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
PLAIN-LANGUAGE APPROACH IN LEGISLATIVE DRAFTING: A PERSPECTIVE FROM POLAND
The purpose of this research is to explore plain-language postulates reflecting on legal drafting assumptions since legal acts should be precise, clear and express with no doubts the intention of the legislator.
Natalia ZYCH
doaj +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Influence of Dumping Bias on Timbral Clarity Ratings
When listening test subjects are required to rate changes in a single attribute, but also hear changes in other attributes, their ratings can become skewed by “dumping bias.” To assess the influence of dumping bias on timbral “clarity” ratings, listeners
Hummersone, C., Brookes, T., Hermes, K.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

