Activation of class 1 integron integrase is promoted in the intestinal environment. [PDF]
PLoS Genetics, 2022 Class 1 integrons are widespread genetic elements playing a major role in the dissemination of antibiotic resistance. They allow bacteria to capture, express and exchange antibiotic resistance genes embedded within gene cassettes.
Murielle Baltazar +7 more
doaj +6 more sources
Transmissible ST3-IncHI2 Plasmids Are Predominant Carriers of Diverse Complex IS26-Class 1 Integron Arrangements in Multidrug-Resistant Salmonella [PDF]
Frontiers in Microbiology, 2018 Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria.
Hang Zhao +4 more
doaj +2 more sources
Environmental Isolate of Rahnella aquatilis Harbors Class 1 Integron. [PDF]
Curr Microbiol, 2016 The paper presents first description of class 1 integron in an environmental strain of Rahnella aquatilis, a rarely isolated Gram-negative bacterium of the family Enterobacteriaceae. The strain was isolated from the Warta river water, Poland. Class 1 integrase gene was detected by a PCR assay.
Koczura R, Mokracka J, Makowska N.
europepmc +4 more sources
Complex Class 1 Integron in a Clinical Escherichia coli Strain From Vietnam Carrying Both mcr-1 and blaNDM–1 [PDF]
Frontiers in Microbiology, 2019 The co-production of MCR and carbapenemase in Enterobacteriaceae has been previously reported. Here, we describe a clinical strain of Escherichia coli from Vietnam carrying both mcr-1 and blaNDM–1.
Hong-Ngoc Le-Vo +9 more
doaj +2 more sources
Polymorphisms of Gene Cassette Promoters of the Class 1 Integron in Clinical Proteus Isolates [PDF]
Frontiers in Microbiology, 2019 ObjectiveTo describe the polymorphisms of gene cassette promoters of the class 1 integron in clinical Proteus isolates and their relationship with antibiotic resistance.MethodsPolymorphisms of the gene cassette promoter in 153 strains of Proteus were ...
Linlin Xiao +13 more
doaj +2 more sources
Antimicrobial Resistance in Class 1 Integron-Positive Shiga Toxin-Producing Escherichia coli Isolated from Cattle, Pigs, Food and Farm Environment [PDF]
Microorganisms, 2018 The aim of this study was to investigate the presence of class 1 integrons in a collection of Shiga toxin-producing Escherichia coli (STEC) from different origins and to characterize pheno- and genotypically the antimicrobial resistance associated to ...
Rocío Colello +7 more
doaj +2 more sources
High prevalence of class 1 integron, biofilm formation, and antimicrobial resistance profiles of Escherichia coli isolated from cattle, water, and soil in Bangladesh [PDF]
BMC MicrobiologyBackground Antimicrobial resistance (AMR) is a global threat. Escherichia coli is an important reservoir of resistance genes, and the coexistence of mcr with class 1 integron (intI1) is alarming, mcr confers resistance to colistin, a last-resort ...
Md. Niamul Shahadat +3 more
doaj +2 more sources
Definition of the attI1 site of class 1 integrons [PDF]
Microbiology, 2000 Integron-encoded integrases recognize two distinct types of recombination site: attI sites, found in integrons, and members of the 59-base element (59-be) family, found in the integron-associated gene cassettes. The class 1 integron integrase, IntI1, catalyses recombination between attI1 and a 59-be, two 59-be, or two attI1 sites, but events involving ...
Sally R, Partridge +5 more
openaire +5 more sources
Class 1 integron in staphylococci [PDF]
Molecular Biology Reports, 2011 As a major concern in public health, methicillin-resistant staphylococci (MRS) still remains one of the most prevalent pathogens that cause nosocomial infections throughout the world and has been recently labeled as a "super bug" in antibiotic resistance.
Zhenbo, Xu +3 more
openaire +2 more sources
Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
openaire +2 more sources