Results 101 to 110 of about 268,103 (267)

Diophantine Equations and Class Numbers

open access: yesJournal of Number Theory, 1986
In this paper, the author intends to extend some already known results. First he tries to provide sufficient conditions for non-trivial class numbers of real quadratic fields of Richaud-Degert type, in order to generalize results of Ankeny-Chowla-Hasse, S. D. Lang, H. Takeuchi and I. Yamaguchi.
openaire   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

On the Characterization of a Class of Difference Equations

open access: yesDiscrete Dynamics in Nature and Society, 2011
We focus on the behavior of solutions of the difference equation xn = b1xn−1 + b2xn−2 + ⋯+bnx0 + yn, n = 1, 2, …, where (bk) is a fixed sequence of complex numbers, and (yk) is a fixed sequence in a complex Banach space. We give the general solution of this difference equation.
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Multiple solutions for a class of Kirchhoff-type equation with critical growth

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
In this paper, we study the multiplicity of solutions to a class of Kirchhoff-type equation with critical growth $$ -\left(a+b\int_{\mathbb{R}^3}|\nabla u|^2dx\right)\Delta u+V(x)u=\lambda h(x)f(u)+g(x)u^5 \quad \mbox{in }\mathbb{R}^3, $$ where $a$, $b ...
Yiwei Ye, Shan Liu
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

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