Results 71 to 80 of about 3,782,951 (354)
Reduced Steenrod operations and resolution of singularities
, 2011 We give a new construction of a weak form of Steenrod operations for Chow groups modulo a prime number p for a certain class of varieties. This class contains projective homogeneous varieties which are either split or over a field admitting some form of ...
Elman +6 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A geometric recipe for twisted superpotentials
Journal of High Energy Physics, 2021 We give a pedagogical introduction to spectral networks and abelianization, as well as their relevance to N $$ \mathcal{N} $$ = 2 supersymmetric field theories in four dimensions.
Lotte Hollands +2 more
doaj +1 more source
Relativistic action at a distance and fields
, 2011 After a brief review of the field formulations and the relativistic non-instantaneous action-at-a-distance formulations of some well known classical theories, we study Rivacoba's generalization of a theory with a linearly rising potential as a ...
Louis-Martinez, Domingo J.
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
New T-duality for Chern-Simons theory
Journal of High Energy Physics, 2019 It has recently pointed out that a four-dimensional analog of Chern-Simons theory provides an elegant framework for understanding integrable models with spectral parameters.
Masahito Yamazaki
doaj +1 more source
6d SCFTs, 5d dualities and Tao web diagrams
Journal of High Energy Physics, 2019 We propose 5d descriptions of 6d N = 1 , 0 $$ \mathcal{N}=\left(1,\ 0\right) $$ superconformal field theories arising from Type IIA brane configurations with an O8−-plane.
Hirotaka Hayashi +3 more
doaj +1 more source
Oscillating bounce solutions and vacuum tunneling in de Sitter spacetime
, 2004 We study a class of oscillating bounce solutions to the Euclidean field equations for gravity coupled to a scalar field theory with two, possibly degenerate, vacua. In these solutions the scalar field crosses the top of the potential barrier $k>1$ times.
Hackworth, James C., Weinberg, Erick J.
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source