Results 191 to 200 of about 20,214,462 (360)

Presentation of identical tumor antigen peptides by canine and human MHC class I. [PDF]

open access: yesiScience
Kaabinejadian S   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

HLA Class I Loss and Resistance to Immunotherapy in Pulmonary Metastasis of Hypopharyngeal Cancer. [PDF]

open access: yesIn Vivo
Murakami A   +6 more
europepmc   +1 more source

The myth of middle-class proletarianisation : Defining and examining class in Sweden from a neo-Marxist perspective

open access: yes
Since the 2007–2008 financial crisis, it has been suggested that the middle class is undergoing proletarianisation, with stagnant wages and reduced work autonomy making their conditions more like those of the working class. However, there is no consensus
Alfonsson, Johan
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Computational design of HLA class I superbinders for broad T cell immunogenicity. [PDF]

open access: yesProc Natl Acad Sci U S A
Peer E   +4 more
europepmc   +1 more source

On classes of summing operators, I

open access: yesProceedings of the Japan Academy, Series A, Mathematical Sciences, 1969
Craiu, V., Istrǎţescu, V.
openaire   +3 more sources

Negotiation and Navigation - an Exploration of the Spaces/Places of Working-Class Lesbians [PDF]

open access: yes
This article draws upon my research on working-class lesbians, which explores the relationship between class, sexuality and social exclusion. Research participants were drawn mainly from Scotland (Glasgow, Edinburgh and the Highlands), with smaller ...
Yvette Taylor
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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