Results 71 to 80 of about 1,846,012 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Discussion Note: Conceptual Problems in Classical Electrodynamics [PDF]
I have argued that the standard ways of modeling classical particle-field interactions rely on a set of inconsistent assumptions. This claim has been criticized in (Muller forthcoming).
Frisch, Mathias
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
This report presents the results of surveillance on transmissible spongiform encephalopathies in cattle, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2023 by 27 Member States (MS, EU27), the United Kingdom ...
European Food Safety Authority (EFSA)
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Seven Steps Towards the Classical World [PDF]
Classical physics is about real objects, like apples falling from trees, whose motion is governed by Newtonian laws. In standard quantum mechanics only the wave function or the results of measurements exist, and to answer the question of how the ...
Duerr, Detlef +3 more
core
Tools for Verifying Classical and Quantum Superintegrability [PDF]
Recently many new classes of integrable systems in n dimensions occurring in classical and quantum mechanics have been shown to admit a functionally independent set of 2n−1 symmetries polynomial in the canonical momenta, so that they are in fact ...
Willard Miller, Jr. +8 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The maximal subgroups of the classical groups in dimension 13, 14 and 15
One might easily argue that the Classification of Finite Simple Groups is one of the most important theorems of group theory. Given that any finite group can be deconstructed into its simple composition factors, it is of great importance to have a ...
Anna Katharina Schröder +1 more
core
Late Classical Chinese Thought
Chris Fraser presents a rich and broad-ranging study of the culminating period of classical Chinese philosophy, the third century BC. He offers novel and informative perspectives on Confucianism, Daoism, Mohism, Legalism, and other movements in early ...
Fraser, Chris
core +1 more source

