Results 121 to 130 of about 247,743 (267)

Heterogeneous associative plasticity in the auditory cortex induced by fear learning - novel insight into the classical conditioning paradigm. [PDF]

Physiol Res, 2021
Zelenka O, Novak O, Brunova A, Syka J.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Toward reconsolidation blockade as a novel treatment for PTSD

European Journal of Psychotraumatology, 2012
Rationale/statement of the problem : Animal research has challenged the permanency of memory by suggesting that reactivation (retrieval) of a specific memory may return it to a labile state from which it must be “re-consolidated” if it is ...
Roger K. Pitman, Alain Brunet, Vadim Bolshakov, Karine Gamache, Karim Nader   +4 more
doaj   +1 more source

Order does matter: the combined effects of classical conditioning and verbal suggestions on placebo hypoalgesia and nocebo hyperalgesia. [PDF]

Pain, 2021
Bajcar EA, Wiercioch-Kuzianik K, Farley D, Buglewicz E, Paulewicz B, Bąbel P.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Discrimination training affects stimulus generalization in mice during Pavlovian eyeblink conditioning

Frontiers in Behavioral Neuroscience
The delicate balance between discrimination and generalization of responses is crucial for survival in our ever-changing environment. In particular, it is important to understand how stimulus discrimination affects the level of stimulus generalization ...
Francesca Romana Fiocchi, Francesca Romana Fiocchi, Nikki E. S. van Dorp, Nikki E. S. van Dorp, Stephanie Dijkhuizen, Maurits van den Berg, Aaron Wong, Chris I. De Zeeuw, Chris I. De Zeeuw, Henk-Jan Boele, Henk-Jan Boele   +10 more
doaj   +1 more source

The Claustrum is Involved in Cognitive Processes Related to the Classical Conditioning of Eyelid Responses in Behaving Rabbits. [PDF]

Cereb Cortex, 2021
Reus-García MM, Sánchez-Campusano R, Ledderose J, Dogbevia GK, Treviño M, Hasan MT, Gruart A, Delgado-García JM.   +7 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Editorial: Neurofeedback in ADHD

Frontiers in Human Neuroscience, 2015
Martijn eArns, Martijn eArns, Hartmut eHeinrich, Hartmut eHeinrich, Tomas eRos, Aribert eRothenberger, Ute eStrehl   +6 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source