Results 41 to 50 of about 35,737 (310)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Mind: Embodied, Embedded, but not Extended [PDF]

open access: yes, 1998
This commentry focuses on the one major ecumenical theme propounded in Andy Clark's Being There that I find difficult to accept; this is Clark’s advocacy, especially in the third and final part of the book, of the extended nature of the embedded ...
O'Brien, Gerard
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Modernism and Muddle: Religious Implications of T. S. Eliot’s Use of the Term

open access: yesE-REA, 2018
Around the year 1930, as noted by Ronald Schuchard, T. S. Eliot moved beyond the opposition of classicism and romanticism, replacing it with a juxtaposition of orthodoxy and modernism.
Anna BUDZIAK
doaj   +1 more source

David Martin: my teacher, or, a way of seeing [PDF]

open access: yes, 2020
David Martin’s sociology of religion embodied an expansive vision of religion, one that encompassed the entirety of human and social experience: its political, national, economic, aesthetic, poetical and spiritual-religious orientations, and the ...
Leoussi, Athena S.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Il Discobolo e la Brillo Box

open access: yesRivista di Estetica, 2016
The idea that the Avant-garde and Classicism are placed at the antipodes of art history is a commonly accepted opinion. However, a deeper analysis proves it to be inconsistent and superficial.
Maurizio Ferraris
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

faust hat hunger und verschluckt sich an einer grete de Ewald Palmetshofer. De la digestion difficile des classiques

open access: yesCahiers d’Études Germaniques, 2013
In 2009, Ewald Palmetshofer presented with his postmodern play faust hat hunger und verschluckt sich an einer grete his own version of Goethe’s Faust, this monument of German Classicism.
Sylvie Arlaud
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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