Results 81 to 90 of about 391,329 (357)
Citation classics in systematic reviews and meta-analyses : who wrote the top 100 most cited articles? [PDF]
, 2013 Background: Systematic reviews of the literature occupy the highest position in currently proposed hierarchies of evidence. The aims of this study were to assess whether citation classics exist in published systematic review and meta-analysis (SRM ...
Clarke, Aileen +4 more
core +6 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Introduction: The Interpretation of Cultures at Fifty
SociologicaIntroducing the symposium “The Interpretation of Cultures at Fifty,” editors Andrea Cossu and Matteo Bortolini reflect on the dynamics of the iconicization of texts and the paradoxical quality of so-called “classics”: their being present while being ...
Andrea Cossu, Matteo Bortolini
doaj +1 more source
Implementation of Values Education based on the Cultural Essence of Ancient Poems and Classics
, 2021 Wang Wen-juan
openalex +2 more sources
Classics Illustrated: Limits of Spacetimes
, 2014 We carefully study the $e \rightarrow m$ and $e \rightarrow 0$ limits of the Reissner-Nordstr\"om spacetime using Geroch's definition of limits of spacetimes. This is implemented by embedding the one-parameter family of spacetimes in anti-de Sitter space,
Bengtsson, Ingemar +2 more
core +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
, 2006 In this JEB Classics paper, Sir James Gray and G. J. Hancock explained how spermatozoa are propelled by flagellar bending waves (Gray and Hancock, 1955). This paper was a lasting success because it provided an easy-to-understand solution to a complicated
Brokaw, Charles J.
core +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source