Design principles for robust vesiculation in clathrin-mediated endocytosis
J. Hassinger+3 more
semanticscholar +1 more source
Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou+6 more
wiley +1 more source
Mechanisms of Carrier Formation during Clathrin-Independent Endocytosis.
Antonio P. A. Ferreira, Emmanuel Boucrot
semanticscholar +1 more source
Mannose 6–Phosphate Receptors Are Sorted from Immature Secretory Granules via Adaptor Protein AP-1, Clathrin, and Syntaxin 6–positive Vesicles [PDF]
Judith Klumperman+4 more
openalex +1 more source
NIR II‐Guided Photoactivatable Silencing Polyplex Boosts Cancer Immunotherapy
Due to limitation of penetration therapy with first and second‐generation photodynamic therapy (PDT) photosensitizers, an NIR II‐guided photoactivatable complex was proposed via the self‐assembly of the photosensitive polymer PTSQ and the electrostatic adsorption of siPD‐L1 to enhance cancer immunotherapy.
Yuquan Zhang+10 more
wiley +1 more source
Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects [PDF]
Diamond, Michael S+2 more
core +2 more sources
Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration
N. Elkhatib+6 more
semanticscholar +1 more source
The Interaction of Epsin and Eps15 with the Clathrin Adaptor AP-2 Is Inhibited by Mitotic Phosphorylation and Enhanced by Stimulation-dependent Dephosphorylation in Nerve Terminals [PDF]
Hong Chen+3 more
openalex +1 more source