Results 241 to 250 of about 115,227 (298)

The Role of the CLIC/GEEC Endocytic Pathway for Mechanophysical Transfection of DNA. [PDF]

J Gene Med
Weaver S, Lallow EO, Kyker-Snowman K, Jhumur NC, Gulley M, Roberts CC, Shreiber DI, Lin H, Maslow JN.   +8 more
europepmc   +1 more source

Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A mechanistic basis is proposed for how variation in protein sequence perturbs cholesterol handling in Niemann–Pick type C2 (NPC2) protein. A relatively rigid hydrophobic core stabilizes cholesterol binding, a flexible but coordinated rim enables controlled access and productive transfer of cholesterol, and coordinated loop motions modulate pocket ...
Smit Patel, Nadia Elghobashi‐Meinhardt
wiley   +1 more source

PIKI-1, a class II PI 3-kinase, functions in endocytic trafficking. [PDF]

PLoS Genet
Reimann GR, Edeen PT, Conquest S, Grant BD, Fay DS.   +4 more
europepmc   +1 more source

Intracellular Localization of PD-L1 in Rab10-positive Open Tubular Endosome System of Cancer Cells. [PDF]

Acta Histochem Cytochem
Yamada R, Sakamoto R, Kawai K, Egami Y, Araki N.   +4 more
europepmc   +1 more source

Rethinking the Yeast Endomembrane System. [PDF]

Subcell Biochem
Glick BS.
europepmc   +1 more source

Histamine H₁ Receptor-Mediated CREB Phosphorylation via G_q Protein Signaling and Arrestin Modulation. [PDF]

Pharmaceuticals (Basel)
Ogami R, Michinaga S, Iiboshi Y, Ogawa Y, Hishinuma S.   +4 more
europepmc   +1 more source

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review). [PDF]

Int J Oncol
Zhang T, Li L, Du C.
europepmc   +1 more source

Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis. [PDF]

Commun Biol
Maestro A, Zaccai NR, Gonzalez-Martinez JF, Sanchez-Puga P, Tajuelo J, Rubio MA, Santamaria A, Carrascosa-Tejedor J, Pereira D, Marín-Montesinos I, Gutfreund P, Campbell R, Kotar J, Kelly BT, Cicuta P, Owen DJ.   +15 more
europepmc   +1 more source

Dynamic GLUT trafficking at high glucose levels enhances insulin secretion: Dysregulation leads to decreased insulin secretion during type 2 diabetes. [PDF]

Proc Natl Acad Sci U S A
Pallavi A, Sinha N, ArunKumar NK, Kothegala L, Gandasi NR.   +4 more
europepmc   +1 more source