Results 331 to 340 of about 135,129 (369)
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Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
Nature Reviews Molecular Cell Biology, 2005The internalization of various cargo proteins and lipids from the mammalian cell surface occurs through the clathrin and lipid-raft endocytic pathways. Protein-lipid and protein-protein interactions control the targeting of signalling molecules and their partners to various specialized membrane compartments in these pathways.
Christine Le Roy
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Endocytic sites mature by continuous bending and remodeling of the clathrin coat
Science, 2015Ori Avinoam +2 more
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Endocytosis without clathrin coats
Trends in Cell Biology, 2001Endocytosis is involved in an enormous variety of cellular processes. To date, most studies on endocytosis in mammalian cells have focused on pathways that start with uptake through clathrin-coated pits. Recently, new techniques and reagents have allowed a wider range of endocytic pathways to begin to be characterized.
B J, Nichols, J, Lippincott-Schwartz
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1999
Abstract Clathrin is a triskelion-shaped, self-assembling protein which polymerizes into a polyhedral lattice on the cytoplasmic surface of cellular membranes. Formation of the clathrin lattice constitutes a mechanism for sorting membrane-associated proteins which are incorporated into the lattice via bridging proteins, known as adaptors
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Abstract Clathrin is a triskelion-shaped, self-assembling protein which polymerizes into a polyhedral lattice on the cytoplasmic surface of cellular membranes. Formation of the clathrin lattice constitutes a mechanism for sorting membrane-associated proteins which are incorporated into the lattice via bridging proteins, known as adaptors
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Nature Cell Biology, 2012
Clathrin adaptor proteins are essential for clathrin-coated vesicle biogenesis, yet the mechanisms governing their recruitment and interactions remain incompletely defined. The clathrin adaptors Gga and AP-1 are now shown to be recruited sequentially to the trans-Golgi network in two waves of clathrin coat assembly, coupled by Pik1-mediated ...
Yidi, Sun, David G, Drubin
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Clathrin adaptor proteins are essential for clathrin-coated vesicle biogenesis, yet the mechanisms governing their recruitment and interactions remain incompletely defined. The clathrin adaptors Gga and AP-1 are now shown to be recruited sequentially to the trans-Golgi network in two waves of clathrin coat assembly, coupled by Pik1-mediated ...
Yidi, Sun, David G, Drubin
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American Journal of Physiology-Cell Physiology, 2000
Subconfluent cultures of Madin-Darby canine kidney (MDCK) and CV-1 cells were immunostained with two monoclonal antibodies (MAbs), MAb X-22 and MAb 23, against clathrin heavy chain and with polyclonal antiserum against a conserved region of all mammalian clathrin light chains.
C T, Okamoto, J, McKinney, Y Y, Jeng
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Subconfluent cultures of Madin-Darby canine kidney (MDCK) and CV-1 cells were immunostained with two monoclonal antibodies (MAbs), MAb X-22 and MAb 23, against clathrin heavy chain and with polyclonal antiserum against a conserved region of all mammalian clathrin light chains.
C T, Okamoto, J, McKinney, Y Y, Jeng
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Clathrin and clathrin-accessory proteins in rat kidney cortex epithelia
Histochemistry and Cell Biology, 2006Several vectorial transport routes in mammalian cells involve clathrin and associated proteins. In kidney epithelia urine production requires numerous transport processes. However, only little is known about the distribution of clathrin and its associated proteins in this organ in situ. We now report on the presence and distribution of clathrin and its
Sabine, Hasse +2 more
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Clathrin, Adaptors, and Sorting
Annual Review of Cell Biology, 1990CONTENTS INTRODUCTION 15 1 COAT COMPONENTS 153 Clathrin Triskelions and Adaptors ....... 153 Function and Distribution of Adaptors 156 COATED PITS AS MOLECULAR FILTERS ......... ... .. 159 Clathrin-Mediated Endocytosis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
B M, Pearse, M S, Robinson
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Driving membrane curvature in clathrin-dependent and clathrin-independent endocytosis
Seminars in Cell & Developmental Biology, 2010Cellular activity depends to a large extent on membrane bilayer dynamics. Many processes, such as organelle biogenesis and vesicular transport, rely on alterations in membrane structure and shape. It is now widely accepted that intracellular membrane curvature generation and remodelling is mediated and regulated by protein action, and the mechanisms ...
Richard, Lundmark, Sven R, Carlsson
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Clathrin and Plant Endocytosis
Traffic, 2002Endocytosis requires the coordinated interaction of a plethora of cytosolic and membrane proteins. In mammalian cells, clathrin plays a crucial role in this process as a scaffolding protein underlying the invaginating plasma membrane and surrounding the primary endocytic vesicle.
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