Results 331 to 340 of about 126,267 (387)

Presynaptic quantal size enhancement counteracts post‐tetanic release depression

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair   +5 more
wiley   +1 more source

Cryo-electron tomography pipeline for plasma membranes. [PDF]

open access: yesNat Commun
Sun WW   +8 more
europepmc   +1 more source

Kif1a and intact microtubules maintain synaptic‐vesicle populations at ribbon synapses in zebrafish hair cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory hair cells of the inner ear and lateral‐line system exhibit strong synaptic‐vesicle enrichment at the presynapse, around specialized structures called ribbons. We find that hair cells in the zebrafish lateral‐line system rely on the kinesin motor protein Kif1a and microtubules to enrich synaptic vesicles at presynaptic ...
Sandeep David   +7 more
wiley   +1 more source

Aged human serum induces vascular changes in an isogenic co-culture venule model. [PDF]

open access: yesStem Cell Reports
Chung TD   +5 more
europepmc   +1 more source

Acute introduction of monomeric or multimeric α‐synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell   +5 more
wiley   +1 more source

An arginine switch drives the stepwise activation of β-arrestin by CXCR7. [PDF]

open access: yesPLoS Biol
Ji JS   +10 more
europepmc   +1 more source

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