Results 131 to 140 of about 21,285,591 (295)
Animal Research and One Health, EarlyView.Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang +11 more
wiley +1 more source
Claudin-1 Is a Valuable Prognostic Biomarker in Colorectal Cancer: A Meta-Analysis
Gastroenterology Research and Practice, 2020 Background. Claudin-1 plays an important part in maintaining the mucosal structures and physiological functions. Several studies showed a relationship between claudin-1 and colorectal cancer (CRC), but its prognostic significance is inconsistent.
Didi Zuo +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.Supplementation with mannan oligosaccharides (MOS) enhances growth, disease resistance, antioxidant capacity, and gut microbiota diversity while suppressing inflammation, apoptosis, and strengthening intestinal barrier integrity in zebrafish challenged with LPS or DSS.
Zhiyuan Lu +4 more
wiley +1 more source
193P CLAUDIN-1 targeting antibodies in solid tumors: From ALE.C04 to CLAUDIN-1 oncology platform
Immuno-Oncology and Technology, 2022 A. Toso +8 more
openaire +1 more source
Predictive value of immunohistochemical expression of claudin-1 in colonic carcinoma
Journal of the Egyptian National Cancer Institute, 2011 Colonic carcinoma is one of the most common cancers worldwide. Recently, the possible involvement of claudin-1, one of the major tight junction proteins, in the process of tumorigenesis has been suggested. Also, claudin-1 has emerged as a potential prognostic factor in different types of tumors.
Abdelzaher, Eman +3 more
openaire +2 more sources
DOCK1 Regulates Growth and Motility through the RRP1B-Claudin-1 Pathway in Claudin-Low Breast Cancer Cells [PDF]
, 2019 Dedicator of cytokinesis 1 (DOCK1) is a critical regulator of cancer metastasis. Claudins are transmembrane proteins that play a role in epithelial barrier integrity.
Ling-Chu Chang +3 more
core +1 more source
Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1
Chemistry – A European Journal, EarlyView.The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang +5 more
wiley +1 more source
Pumilio-1 mediated translational control of claudin-5 at the blood-brain barrier
Fluids and Barriers of the CNSClaudin-5 is one of the most essential tight junction proteins at the blood-brain barrier. A single nucleotide polymorphism rs10314 is located in the 3’-untranslated region of claudin-5 and has been shown to be a risk factor for schizophrenia.
Yosuke Hashimoto +7 more
doaj +1 more source
Cancer Nexus, EarlyView.ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang +4 more
wiley +1 more source
Acute exposure to 27.12 MHz radiofrequency electromagnetic field disrupts blood-brain barrier integrity via eNOS activation and occludin down-regulation [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Controlled modulation of blood-brain barrier (BBB) permeability without inducing damage represents a promising strategy for enhancing central nervous system drug delivery.Materials and Methods: This study investigated the effects of 27.12 ...
Arzu Ulusoy +7 more
doaj +1 more source