Results 201 to 210 of about 21,285,591 (295)

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury. [PDF]

Tissue Barriers
Gowrikumar S, Tarudji A, McDonald BZ, Balusa SS, Kievit FM, Dhawan P.   +5 more
europepmc   +1 more source

Glaesserella parasuis serotype 5 breaches the porcine respiratory epithelial barrier by inducing autophagy and blocking the cell membrane Claudin-1 replenishment. [PDF]

PLoS Pathog, 2022
Liu M, Wang Q, Wu W, Chen M, Zhang P, Guo M, Lin H, Ma Z, Zhou H, Fan H.   +9 more
europepmc   +1 more source

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, EarlyView.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

The Role of Claudin-1 in Enhancing Pancreatic Cancer Aggressiveness and Drug Resistance via Metabolic Pathway Modulation. [PDF]

Cancers (Basel)
Kyuno D, Asano H, Okumura R, Takasawa K, Takasawa A, Konno T, Nakamori Y, Magara K, Ono Y, Imamura M, Kimura Y, Kojima T, Osanai M.   +12 more
europepmc   +1 more source

Moesin, a Cytoskeletal‐Associated Protein, Outperforms Candidate Biomarkers in Identifying Asthma Exacerbation

Allergy, EarlyView.
Pureun‐Haneul Lee, SangMin Yoon, Cheolgi Lee, An‐Soo Jang   +3 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1. [PDF]

Int J Med Sci, 2022
Xie Y, Tan J, Qin Y, Cao Y, Wang Y, Li A, Wang Z, Qiao Z, Yan Z.   +8 more
europepmc   +1 more source

Perineurioma‐like EMA‐positive calvarial neoplasms: clinicopathological study of eight cases

Histopathology, EarlyView.
Perineurioma‐like, EMA‐positive calvarial neoplasms (PLECN) are a rare group of intraosseous spindle cell tumours that demonstrate overlapping morphologic features of perineurioma and fibroblastic meningioma. These lesions tend to behave indolently but show a propensity for progressive growth.
Raheel Rizwan, Yingting Mok, Josephine K Dermawan, Alexandra Isaacson, Veronica Ulici, Scott E Kilpatrick, John D Reith, Gabrielle Yeaney, Hakan Ilaslan, Karen J Fritchie   +9 more
wiley   +1 more source

Expression of Cyclin D1 and Claudin-1 in Invasive Breast Carcinoma and Their Correlation with Clinicopathological Parameters. [PDF]

Iran J Pathol
Sehrawat R, Dhawan V, Roy M, Kediya A, Nijhawan VS.   +4 more
europepmc   +1 more source