Results 191 to 200 of about 78,811 (306)

Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier   +6 more
wiley   +1 more source

Genetic Insights Into Allergic Contact Dermatitis: Reassessing the Role of LCE3C_LCE3B Deletion

open access: yesContact Dermatitis, Volume 94, Issue 3, Page 226-233, March 2026.
This study found no significant association between the LCE3C_LCE3B deletion and allergic contact dermatitis or polysensitisation in Tunisian patients, suggesting that other genetic or environmental factors may contribute to disease susceptibility. ABSTRACT Background Allergic contact dermatitis (ACD) is a multifactorial inflammatory skin disorder ...
Zeineb Ben Lamine   +10 more
wiley   +1 more source

Bulk RNA sequencing dataset of Claudin-low breast cancer cell lines with Neuropilin-1 knockdown. [PDF]

open access: yesSci Data
Lynam LR   +8 more
europepmc   +1 more source

Claudin-Claudin Interactions, Practical Examples

open access: yesBiomedical Journal of Scientific & Technical Research
openaire   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

Porphromonas gingivalis infection induces gingipain-dependent changes in the brain vasculature of zebrafish larvae. [PDF]

open access: yesCell Commun Signal
Mieszkowska A   +4 more
europepmc   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

open access: yesAdvanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava   +9 more
wiley   +1 more source

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