Results 21 to 30 of about 2,543,810 (186)
BEL-1, a novel clavulanic acid-inhibited extended-spectrum ß-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa [PDF]
, 2005 Screening by a double-disk synergy test identified a Pseudomonas aeruginosa isolate that produced a clavulanic acid-inhibited expanded-spectrum β-lactamase (ESBL).
Nordmann, P. +4 more
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The Scientific World Journal, 2002 The aims of this investigation were to calculate the pharmacokinetic parameters and to identify parameters, based on individual plasma concentration-time curves of amoxicillin and clavulanic acid in cats, that may govern the observed differences in ...
Tom B. Vree +2 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2014 The objective of this study was to investigate the formation and forming mechanism of the related substance E in potassium clavulanate production. The impurity with retention time of 11.1 min in potassium clavulanate final product was confirmed as the ...
Chuanqing Zhong +3 more
doaj +1 more source
, 2018 Objectives Bioequivalence (BE) criteria for amoxicillin–clavulanic acid (Co-amoxiclav) oral formulations are based on 90% confidence interval for both amoxicillin and clavulanic acid.
Areeg Anwer Ali +2 more
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Human pharmacokinetics and CSF penetration of clavulanic acid [PDF]
, 1981 Clavulanic acid, a product of Streptomyces clavuligerus with β-lactam structure, is a potent inhibitor of several β-lactamases. To study its pharmacokinetic and CSF penetration in patients without meningeal inflammation, a single oral dose of 250 mg of ...
Siegenthaler, W +3 more
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A Two-component Regulatory System Involved in Clavulanic Acid Production
, 2008 A pair of genes encoding the bacterial two-component regulatory system, orf22 and orf23, was found next to the clavulanic acid gene cluster of Streptomyces clavuligerus NRRL3585. Orf23 was deleted for the construction of S.
Byoung Chul Park +8 more
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Infection and Drug Resistance, 2021 Mingjia Peng,1,2 Renru Han,1,2 Yan Guo,1,2 Yonggui Zheng,1,2 Feifei Yang,1,2 Xiaogang Xu,1,2 Fupin Hu1,2 1Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Key Laboratory of Clinical Pharmacology ...
Peng M +6 more
doaj
An evaluation of the pharmacokinetic safety and efficacy of ticarcillin/clavulanic acid in the treatment of bacterial infections in hospitalized elderly subjects [PDF]
, 1986 dissertationThe geriatric population has an increased incidence of infections, which results in appreciable morbidity and mortality. Alterations in host defense mechanisms with aging contribute to the increased risk of infection.
Roost, Charlotte
core
Amoxicillin/Clavulanic Acid-Induced Thrombocytopenia
, 2016 Introduction and Objective: Drug-induced thrombocytopenia is a common adverse effect reported in the literature. Typically patients present with a low platelet count with signs and symptoms ranging from bruising to bleeding, and major organ damage ...
Saad, Aline +3 more
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Electronic Journal of Biotechnology, 2017 Background: Streptomyces clavuligerus was the producer of clavulanic acid, claR, a pathway-specific transcriptional regulator in S. clavuligerus, positively regulates clavulanic acid biosynthesis.
Ronghuo Qin +5 more
doaj +1 more source